MD
Department of Pediatric Hematology, Amsterdam UMC location University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands
Amsterdam, Noord-Holland, Netherlands
Ilja Oomen is a PhD-candidate at the department of Pediatric Hematology at the Emma Children’s Hospital at the Amsterdam University Medical Center at the University of Amsterdam, the Netherlands under supervision of Prof. Karin Fijnvandraat, MD, PhD and Samantha Gouw, MD, PhD.
She received her medical degree from the University of Amsterdam in 2019. She started her research career on pharmacokinetic and pharmacodynamics effect of anti-rituximab antibodies in children with immune-mediated diseases at the department of pediatric rheumatology.
Her current research focusses on anti-FVIII antibodies and immune tolerance induction (ITI) therapy in patients with hemophilia A. She coordinates an international ITI Steering Group with investigators from Europe, Brazil and Canada that excutes research to identify determinants of ITI success. She recently developed a clinical prediction model based on predictors for the outcome of immune tolerance induction, to tailor therapies according to each patient’s individual chance of success. Additionally, she investigated the immunological mechanism underlying immune tolerance induction, with a cross-interaction of toll-like receptors and Fc gamma receptors with FVIII-immune complexes. Her laboratory training is mentored by Jan Voorberg, professor in cellular hemostasis at Sanquin Research in Amsterdam.
OC 41.6 - Inhibitors, genetics and mechanisms
Monday, June 24, 2024
14:45 – 16:00 ICT
OC 61.2 - Determinants of successful immune tolerance induction in people with severe hemophilia A
Tuesday, June 25, 2024
15:00 – 15:15 ICT