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Anne Angelillo-Scherrer, MD

Head of Department
Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland. Department for BioMedical Research, University of Bern, Murtenstrasse 40, CH-3010 Bern, Switzerland
Bern, Bern, Switzerland

Prof. Anne Angelillo-Scherrer is full professor of medicine at the University of Bern (Switzerland) and Head of the Department of Hematology at the Bern University Hospital since 2013. She is also co-director of the European Haemophilia Comprehensive Care Centre for adult patients at the Bern University Hospital and coordinates the BLOOD Research Program at the Department for BioMedical Research (University of Bern).

She started her medical career at the University of Geneva where she qualified in medicine and obtained the title of specialist in internal medicine and hematology (FMH) at the University Hospital of Geneva in 1999.

Anne Angelillo-Scherrer has more than 20 years of experience in experimental and translational medicine. Her primary research focus lies in the characterization of Gas6 and protein S pathways, crucial molecular pathways within the realms of hemostasis, thrombosis, and inflammation. Within her research laboratory, the in vivo role of protein S, a significant natural anticoagulant, has been examined. The group showed that platelet protein S plays a specific role in regulating venous thrombosis, distinguishing it from arterial thrombosis. These findings underscore the broader concept of the in vivo functionality of anticoagulant factors present in platelets. Furthermore, the Angelillo-Scherrer laboratory has showcased protein S as a therapeutic target for treating hemophilia and other bleeding disorders. The lab has also pioneered the development of a small interfering RNA conjugated to GalNAc ligand to exclusively target protein S gene expression in hepatocytes for therapeutic purposes. Recent research in the lab has revealed the beneficial effects of targeting protein S on bone and joint health within the context of hemophilia.

Since 2017, Anne Angelillo-Scherrer is member of the Swiss National Research Council and since 2018, member of the Senate of the Swiss Academy for Medical Sciences. She is currently president of the Swiss Society of Hematology.

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