OC 67 - Infection and immunothrombosis

Moderator(s)

• 

  Vijay Bhoj, MD PhD

  University of Pennsylvania
• 

  Mirta Schattner, PhD

  Director
  Laboratory of Experimental Thrombosis and Immunobiology of Inflammation, IMEX-CONICET, National Academy of Medicine, Buenos Aires, Argentina.
  Ciudad Autónoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina

Presentations:

• 14:45 – 15:00 ICT

  Ticagrelor targets the cell envelope of Gram-positive bacteria and retains activity against multidrug resistant Staphylococcus aureus
  

  Co-Author: Kirsten Leeten – University of Liège

  Co-Author: Nicolas Jacques – University of Liège

  Co-Author: Lidia Alejo Esquembre – University of Tübingen

  Co-Author: Dana Schneider – University of Tübingen

  Co-Author: Linda Maria Westermann – University of Tübingen

  Co-Author: Jan Bornikoel – University of Tübingen

  Co-Author: Jan Straetner – University of Tübingen

  Co-Author: Camilla Henriksen – University of Copenhagen

  Co-Author: Lucia Musumeci – University of Liège

  Co-Author: Elena Sánchez López – University of Leiden

  Co-Author: Martin Giera – University of Leiden

  Co-Author: Noémie Penoy – University of Liège

  Co-Author: Géraldine Piel – University of Liège

  Co-Author: Olivier Verlaine – University of Liège

  Co-Author: Bernard Joris – University of Liège

  Co-Author: Christoph J. Slavetinsky – University of Tübingen

  Co-Author: Dorte Frees – University of Copenhagen

  Co-Author: Heike Brötz-Oesterhelt – University of Tübingen

  Co-Author: Patrizio Lancellotti – University of Liège

  Presenting Author: Cecile Oury, PhD – Université de Liège
• 15:00 – 15:15 ICT

  Platelet factor 4 aggregates bacteria, modulating bacterial clearance, coagulopathy and the inflammatory milieu, improving sepsis outcomes
  

  Presenting Author: Anh Ngo, PhD – Children's Hospital of Philadelphia

  Co-Author: Hyunjun Kim – The Children's Hospital of Philadelphia

  Co-Author: Veronica Bochenek, BA – Children's Hospital of Philadelphia

  Co-Author: Nate Levine – University of Pennsylvania

  Co-Author: Santosh Yadav – Children's Hospital of Philadelphia

  Co-Author: Amrita Sarkar, PhD – Children's Hospital of Philadelphia

  Co-Author: Lubica Rauova – Children's Hospital of Philadelphia

  Co-Author: Anna Kowalska – Children's Hospital of Philadelphia

  Co-Author: Mortimer Poncz, MD – Children's Hospital of Philadelphia

  Co-Author: Kandace Gollomp – Children's Hospital of Philadelphia
• 15:15 – 15:30 ICT

  Thrombin activatable fibrinolysis inhibitor downregulation prevents fibrinolysis shutdown and improves disease severity in SARS-CoV-2 infected K18-hACE2 mice.
  

  Presenting Author: Roberto Aiolfi, PhD – The Scripps Research Institute

  Co-Author: Hiroshi Deguchi – The Scripps Research Institute

  Co-Author: Jose A. Fernández – The Scripps Research Institute

  Co-Author: Jeanine Ahmed – The Scripps Research Institute

  Co-Author: Miriam Hauer-Jensen – The Scripps Research Institute

  Co-Author: Juan Carlos de la Torre – The Scripps Research Institute

  Co-Author: Laurent O. Mosnier – Scripps Research
• 15:30 – 15:45 ICT

  Thrombin as an initiator, driver, and effector mechanism of lung pathology following bacterial and viral infection
  

  Presenting Author: Laura C. Godin, HBSc – Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Canada

  Co-Author: Agostina Carestia – Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Canada

  Co-Author: Rachelle P. Davis – Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Canada

  Co-Author: Madison Turk – Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Canada

  Co-Author: Esha Kaul – Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Canada

  Co-Author: Shahnas M. Najimudeen – Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada

  Co-Author: Ishara M Isham – Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada

  Co-Author: Mohamed Faizal Abdul-Careem – Faculty of Veterinary Medicine, University of Calgary, Calgary, Canada

  Co-Author: Justin Deniset – Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Canada

  Co-Author: Craig N. Jenne, PhD – Department of Microbiology, Immunology, and Infectious Diseases, University of Calgary, Calgary, Canada
• 15:45 – 16:00 ICT

  Neutrophils critically influence thrombus growth and architecture by enhanced neutrophil-platelet interactions and their reciprocal recruitment during sepsis.
  

  Presenting Author: Bastian Just, M.Sc. – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany

  Co-Author: Lukas Weiss – University Hospital Würzburg, Institute of Experimental Biomedicine I, Würzburg, Germany, University Hospital Würzburg, Department of Internal Medicine I, Würzburg, Germany

  Co-Author: Maria Drayss – University Hospital Würzburg, Institute of Experimental Biomedicine I, Würzburg, Germany, University Hospital Würzburg, Department of Internal Medicine I, Würzburg, Germany

  Co-Author: Johanna Brandt – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany

  Co-Author: Kristina Mott – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany

  Co-Author: Harald Schulze – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany