OC 27 - Laboratory testing in bleeding disorders

Moderator(s)

• 

  Yesim Dargaud, MD, PhD

  Lyon University Hospitals
• 

  Sanna R. Rijpma, PhD

  Clinical chemist
  Laboratory of Hematology, Department of Laboratory Medicine, Radboud university medical center, Nijmegen, the Netherlands
  Nijmegen, Gelderland, Netherlands

Presentations:

• 14:45 – 15:00 ICT

  Dominant negative effects of Gln50Arg mutation in the EGF-1 domain of factor IX causes severe Hemophilia B affecting factor IX replacement therapy
  

  Presenting Author: T. T. van Duijl, T.T. – Molecular Hematology, Sanquin Research, Asterdam, The Netherlands

  Co-Author: Kyra N. Smit – Department of Laboratory medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands

  Co-Author: Nadia Freato – Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands

  Co-Author: Joost C.M. Meijers – Department of Experimental Vascular Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.

  Co-Author: Alette Kooiker – Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands

  Co-Author: Marlene Beijlevelt, MSc – Amsterdam UMC

  Co-Author: Henrike M. Hamer – Department of Laboratory medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands

  Co-Author: Maartje van den biggelaar – Molecular Hematology, Sanquin Research, Amsterdam, The Netherlands

  Co-Author: Samantha C. Gouw, MD PhD – Department of Pediatric Hematology, Emma Children’s Hospital, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands
• 15:00 – 15:15 ICT

  Comparing thrombin generation in hemophilia A and patients with non-valvular atrial fibrillation on vitamin K antagonists
  

  Presenting Author: Daniel Kraemmer, MD – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Cihan Ay, MD – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Judit Rejtő – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Peter Quehenberger – Department of Laboratory Medicine, Medical University of Vienna

  Co-Author: Ingrid Pabinger – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Oliver Königsbrügge, MD PhD – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna
• 15:15 – 15:30 ICT

  Whole-blood rotational thromboelastometry in patients with bleeding disorder of unknown cause
  

  Presenting Author: Dino Mehic – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Tim Dreier, MD – Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Jasmin Rast – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Christa Drucker – Department of Clinical Pharmacology

  Co-Author: Bernd Jilma, MD – Department of Clinical Pharmacology, Medical University Vienna

  Co-Author: Cihan Ay, MD – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Ingrid Pabinger – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna

  Co-Author: Johanna Gebhart – Department of Internal Medicine I, Clinical Division of Hematology and Haemostaseology, Medical University of Vienna
• 15:30 – 15:45 ICT

  Wide Individual variation of emicizumab concentrations and surrogate factor VIII activity assessed by human factor-based chromogenic substrate assay in hemophilia A patients without inhibitor
  

  Presenting Author: Masato Bingo, MD, PhD – Department of Laboratory medicine, Tokyo Medical University

  Co-Author: Azusa Nagao, MD, MSc, PhD – Department of Blood Coagulation, Ogikubo Hospital

  Co-Author: Yoshiyuki Ogawa – Department of Hematology, Gunma University Graduate School of Medicine

  Co-Author: Haruka Uemura – AIDS Clinical Center, National Center for Global Health and Medicine

  Co-Author: Junji Imamura – Department of Infectious Diseases, National Hospital Organization Sendai Medical Center

  Co-Author: Katsuyuki Fukutake – Department of Blood Coagulation, Ogikubo Hospital

  Co-Author: Hiroshi Handa – Department of Hematology, Gunma University Graduate School of Medicine

  Co-Author: Toshihiro Ito – Department of Infectious Diseases, National Hospital Organization Sendai Medical Center

  Co-Author: Keiko Shinozawa, PhD – Department of Laboratory Medicine, Tokyo Medical University/Japan

  Co-Author: Hiroshi Inaba – Department of Laboratory Medicine, Tokyo Medical University

  Co-Author: Ei Kinai – Department of Laboratory Medicine, Tokyo Medical University
• 15:45 – 16:00 ICT

  Impact of differential binding of recombinant factor VIII concentrates to platelets on platelet clotting functionality
  

  Co-Author: Anja Strebel – Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zurich

  Co-Author: Fabrizio A. Pennacchio – Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH

  Co-Author: Alessandro Bossoni – Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zurich

  Co-Author: Sebastien Lickert – Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zurich

  Co-Author: Robert Klamroth, MD – Vivantes Klinikum, Friedrichshain, Berlin, Germany

  Presenting Author: Viola Vogel, Prof. Dr. Dr. hc – Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zurich