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Oral Communication Session
Oral Communication Session

OC 26 - TTP: Animal model to real-world data

Sunday, June 23, 2024
14:45 – 16:00 ICT
Room:111 A-C

    Moderator(s)

  • Bernd Jilma, MD

    Professor
    Department of Clinical Pharmacology, Medical University Vienna
    Vienna, Wien, Austria

  • Pavan Bendapudi, MD

    Research Assistant Professor
    Harvard Medical School
    Boston, Massachusetts, United States

Presentations:

  • 14:45 – 15:00 ICT
    A novel rat model of spontaneous thrombotic thrombocytopenia Purpura Reveals a Critical Role of ADAMTS13 in Fetal Health

    Presenting Author: Quan Zhang, MD – The University of Kansas Medical Center

    Co-Author: Liang Zheng, PhD – University of Kansas Medical Center

    Co-Author: Aria Triska – University of Kansas Medical Center

    Co-Author: Joshua Muia, PhD – Versiti Blood Research Institute

    Co-Author: Michael J. Soares – University of Kansas Medical Center

    Co-Author: Long Zheng, MD, PhD – University of Kansas Medical Center

  • 15:00 – 15:15 ICT
    Bortezomib for rituximab-refractory immune-mediated thrombotic thrombocytopenic purpura in the caplacizumab era: update of an Italian multicenter study

    Presenting Author: Juri Alessandro Giannotta, Medical Doctor – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Andrea Artoni – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Ilaria Mancini – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Monica Carpenedo – UOC Ematologia e SIMT, ASST Fatebenefratelli-Sacco, Ospedale L. Sacco, Polo Didattico Università degli Studi di Milano, Milan, Italy

    Co-Author: Addolorata Truma, MD – Università degli studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy.

    Co-Author: Pasquale Agosti, MD, PhD – Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.

    Co-Author: Barbara Ferrari – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Pasqualina De Leo – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Prassede Salutari – Hematology Unit, Department of Oncology and Hematology, Spirito Santo Hospital, Pescara, Italy

    Co-Author: Giorgia Mancini – Hematological Unit, Polytechnic Marche University, Ancona, Italy

    Co-Author: Alfredo Molteni – UOC Ematologia e CTMO, ASST Cremona, Cremona, Italy

    Co-Author: Erminia Rinaldi – Hematology Unit, A. Perrino Hospital, Brindisi, Italy

    Co-Author: Monica Bocchia – Hematology Unit, Azienda Ospedaliero-Universitaria Senese, University of Siena, Siena, Italy

    Co-Author: Mariasanta Napolitano – PROMISE Department, University of Palermo, Palermo, Italy

    Co-Author: Lucia Prezioso – Hematology and BMT Unit, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy

    Co-Author: Annarosa Cuccaro – Hematology Unit, Center for Translational Medicine, Azienda USL Toscana NordOvest, Livorno, Italy

    Co-Author: Elisabetta Scarpa – Hematology Department and Transfusion Service, Castelfranco Veneto Regional Hospital, Castelfranco Veneto, Italy

    Co-Author: Annalisa Condorelli – Department of Hematology, ASST Papa Giovanni XXIII, Bergamo, Italy

    Co-Author: Daniele Grimaldi – Hematology Division, AO S. Croce e Carle, Cuneo, Italy

    Co-Author: Flora Peyvandi, MD, PhD – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Università degli Studi di Milano, Department of Pathophysiology and Transplantation

  • 15:15 – 15:30 ICT
    PLASMIC score to differentiate TTP from other causes of microangiopathic haemolytic anaemia

    Presenting Author: Sobia Sharif, MBBS, MA (Medical Law and Ethics), MRCP, FRCPath – Royal London Hospital

    Co-Author: Marie Scully – University College London

    Co-Author: Andrew J Doyle – Haemostasis & Thrombosis Centre, St Thomas’ Hospital, London, UK

    Co-Author: Matthew Carter – Addenbrookes Hospital

    Co-Author: Saima Afridi – Guys and St Thomas' NHS Foundation Trust

  • 15:30 – 15:45 ICT
    Questioning the benefit of Caplacizumab for the treatment of acquired Thrombotic Thrombocytopenic Purpura: a real-world, single center experience

    Presenting Author: Sheh-Li Chen, PharmD – Pharmacy

    Co-Author: Brian Lam – University of North Carolina Hospitals

    Co-Author: Madeline Ganter – University of North Carolina Hospitals

    Co-Author: Sendy Lin – University of North Carolina Eshelman School of Pharmacy

    Co-Author: Raj Kasthuri – Division of Hematology, University of North Carolina at Chapel Hill

  • 15:45 – 16:00 ICT
    Predisposing conditions and drugs to caplacizumab-related bleeding episodes in patients with acute immune-mediated TTP: real-world data from the Milan Center

    Presenting Author: Pasquale Agosti, MD, PhD – Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.

    Co-Author: Matilde Reichenbach – Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy

    Co-Author: Ilaria Mancini – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Pasqualina De Leo – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Giulia Maria Giorgia Lo Piano – Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy.

    Co-Author: Addolorata Truma, MD – Università degli studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy.

    Co-Author: Juri Alessandro Giannotta, Medical Doctor – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Barbara Ferrari – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Andrea Artoni – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy

    Co-Author: Flora Peyvandi, MD, PhD – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Università degli Studi di Milano, Department of Pathophysiology and Transplantation