LB 01 - Late-Breakthrough Session

Moderator(s)

• 

  Christopher Ward, BMedSc MBChB PhD FRACP FRCPA

  Clinical Director, Division of Cancer Haematology and Palliative Care
  Royal North Shore Hospital
  Northern Sydney Local Health District/University of Sydney
  St Leonards, New South Wales, Australia
• 

  Flora Peyvandi, MD, PhD

  Full Professor
  Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Università degli Studi di Milano, Department of Pathophysiology and Transplantation
  Milan, Lombardia, Italy

Presentations:

• 09:30 – 09:45 ICT

  Safety, tolerability, and efficacy of mezagitamab (TAK-079) in chronic or persistent primary immune thrombocytopenia: Interim results from a phase 2, randomized, double-blind, placebo-controlled study
  

  Presenting Author: David J. Kuter, MD, DPhil – Hematology Division, Massachusetts General Hospital, Harvard Medical School

  Co-Author: Dražen Pulanić – Thrombosis and Benign Hematology Disorders, Division of Hematology, Department of Internal Medicine, University Hospital Center Zagreb

  Co-Author: Andrea Patriarca – AOU Maggiore della Carità and University of Eastern Piedmont

  Co-Author: Renchi Yang, MD – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

  Co-Author: Katya Sapunarova – Department of Hematology, Medical University of Plodiv

  Co-Author: Katsuhiro Miura – Department of Hematology and Oncology, Nihon University Itabashi Hospital

  Co-Author: MK Farmer – Takeda Development Center Americas, Inc.

  Co-Author: Scarlett Wang – Takeda Development Center Americas, Inc.

  Co-Author: Aimee Sundberg – Takeda Development Center Americas, Inc.
• 09:45 – 10:00 ICT

  Engineering FVIII protein for enhancing expression and secretion profile to achieve normal level of FVIII in plasma utilizing noninvasive transcutaneous ultrasound mediated gene delivery.
  

  Presenting Author: Ivan Krivega, PhD – SonoThera

  Co-Author: Ivan Krivega – SonoThera

  Co-Author: Julia Poniatowski – Sonothera

  Co-Author: David Kim – SonoThera

  Co-Author: Elizabeth Del Greco – SonoThera

  Co-Author: Surabhi Rao – SonoThera

  Co-Author: Victor Foster – SonoThera

  Co-Author: Bert Frederich – SonoThera

  Co-Author: Barry Campbell – SonoThera

  Co-Author: Adel Alonso – SonoThera

  Co-Author: Glenda Arauz – SonoThera

  Co-Author: Celia Ortiz – SonoThera

  Co-Author: Oliver Chen – SonoThera

  Co-Author: Dhruv Bole – SonoThera

  Co-Author: Katie Benthal – SonoThera

  Co-Author: Anagha Rao – SonoThera

  Co-Author: David Satyadi – SonoThera

  Co-Author: Zoya Gluzman-Poltorak – SonoThera

  Co-Author: Steve Feinstein – SonoThera

  Co-Author: Kenneth Greenberg – SonoThera
• 10:00 – 10:15 ICT

  Evaluation of Recombinant Human Prourokinase in the Treatment of Acute Pulmonary Embolism (ERUPTE): A Randomized, Single-Blinded, Multicenter, Phase 2 Trial
  

  Presenting Author: Zhi-Cheng Jing, MD – Guangdong Cardiovascular Institute，Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University

  Co-Author: Chun-Yan Cheng – Department of CardioVascular Medicine, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences

  Co-Author: Xin Jiang – Department of CardioVascular Medicine, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences

  Co-Author: Rui Liu – taslypharma

  Co-Author: Duo-Lao Wang – Liverpool School of Tropical Medicine
• 10:15 – 10:30 ICT

  EMA601, a Novel Humanised Fab Inhibits Platelet Glycoprotein VI with Unprecedented Potency and Protects Mice from Arterial Thrombosis and Ischemic Stroke
  

  Presenting Author: Stefano Navarro, PhD – Universitätklinikum Würzburg

  Co-Author: Ivan Talucci – University Hospital Würzburg

  Co-Author: Vanessa Göb – 5Institute for Experimental Biomedicine, University Hospital Würzburg

  Co-Author: Stefanie Hartmann – University Hospital Würzburg

  Co-Author: Sarah Beck – Universitätklinikum Würzburg

  Co-Author: Valerie Orth – Emfret Analytics

  Co-Author: Guido Stoll – University Hospital Wuerzburg

  Co-Author: Hans M. Maric – University of Wuerzburg

  Co-Author: David Stegner – Institute for Experimental Biomedicine, University Hospital Würzburg

  Co-Author: Bernhard Nieswandt – University Hospital Würzburg
• 10:30 – 10:45 ICT

  Efficacy and safety of Mim8 prophylaxis in adults and adolescents with hemophilia A with or without inhibitors: Phase 3, open-label, randomized, controlled FRONTIER2 study
  

  Presenting Author: Maria Elisa Mancuso, MD, PhD – Centre for Thrombosis and Haemorrhagic Diseases, IRCCS Humanitas Research Hospital

  Co-Author: Tadashi Matsushita – Nagoya University Hospital, Nagoya, Japan

  Co-Author: Pratima Chowdary, MD – Katharine Dormandy Haemophilia and Thrombosis Centre, Royal Free Hospital

  Co-Author: Steven R. Lentz – The University of Iowa Carver College of Medicine

  Co-Author: Johnny Mahlangu, MBBCh, MMed – Department of Molecular Medicine and Haematology, University of the Witwatersrand, National Health Laboratory Service, and Charlotte Maxeke Johannesburg Academic Hospital

  Co-Author: Chandrakala Shanmukhaiah – Department of Clinical Hematology, Seth G.S.M.C and K.E.M. Hospital

  Co-Author: Ilgiz Rakhmatullin – Novo Nordisk A/S

  Co-Author: Pernille Juul Jørgensen – Novo Nordisk A/S

  Co-Author: Johannes Oldenburg, MD – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine