Ciara Byrne, PhD

Postdoc
RCSI Dublin
Dublin, Dublin, Ireland

My name is Ciara Byrne and I am a postdoctoral researcher in the Royal College of Surgeons in Ireland. I am currently researching Von Willebrand factor, its clearance and its functions. My PhD was focusing on haemophilia and factor viii knockout mice. Currently, I work mainly with in vivo and ex vivo techniques but also have experience with in vitro methods. I am particularly interested in modulators of VWF levels in people, thrombosis and the VWF-inflammation axis but I also retain a passion for FVIII inhibitors and FVIII biology.

Presentation(s):

• OC 15.2 - N-glycans located in the VWF-A2 domain regulate A1-domain mediated clearance through macrophage LRP1 and SR-A1 receptors

  Sunday, June 23, 2024
  09:45 – 10:00 ICT

• OC 15.3 - Terminal sialylation of commercial rVWF concentrate is responsible for attenuated macrophage-mediated clearance via the MGL receptor.

  Sunday, June 23, 2024
  10:00 – 10:15 ICT

• PB0337 - VWF binding to galectin-1 and -3: VWF glycosylation and implication on its function

  Sunday, June 23, 2024
  13:45 – 14:45 ICT