Research director
Inserm UMR-S1255
Strasbourg, Alsace, France
Dr Yotis Senis was awarded a BScH in Life Sciences in 1993, an MSc in 1996 and a PhD in 2002 in Pathology at Queen’s University, Canada. His PhD was on the regulation of haematopoietic cell development and function by the protein-tyrosine kinases (PTKs) Fps and Fer, under the supervision of Professor Peter Greer. In 2002 he joined the laboratory of Professor Steve Watson in Pharmacology at the University of Oxford, UK as a postdoctoral researcher, characterizing novel receptors and signalling pathways regulating platelet activation and thrombosis. In 2003 he was appointed Research Fellow in Physiology at the University of Birmingham, UK, and started investigating the functional roles of protein-tyrosine phosphatases (PTPs), notably the receptor-type PTPRJ (CD148) in platelet activation and thrombosis. He was awarded a British Heart Foundation Intermediate Basic Science Research Fellowship in 2009, followed by a Senior Fellowship in 2013 investigating the co-inhibitory receptor G6b-B and non-transmembrane PTPs Shp1 and Shp2 in platelet homeostasis. He was promoted to Chair in Cellular Haemostasis in the College of Medical and Dental Sciences at the University of Birmingham in 2013. In 2019 he was appointed Director of Research at the Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche-S 1255, Strasbourg, France. In his research, Dr Senis takes a multidisciplinary approach investigating how PTPs work in conjunction with PTKs to regulate the threshold of platelet production and activation in health and disease, with the overall objective of developing novel anti-platelet therapies and strategies for culturing platelets.
Monday, June 24, 2024
09:30 – 09:45 ICT
SOA 20.4 - The platelet signaling landscape
Tuesday, June 25, 2024
08:00 – 09:15 ICT