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Prithu Sundd

Professor
Versiti Blood Research Institute
Milwaukee, Wisconsin, United States

I am the Senior Investigator in the Thrombosis and Hemostasis Program at the VERSITI Blood Research Institute (VBRI) and the Blood Center of Wisconsin, and Professor of Medicine (Hematology & Oncology) and Biomedical Engineering at the Medical College of Wisconsin. The overarching goal of my research program is to study the role of thrombo-inflammation, primarily looking at neutrophil-platelet-dependent immune signaling. My lab at VBRI is currently working to elucidate the cellular, molecular and biophysical mechanisms of pulmonary thrombo-inflammation, vascular dysfunction and lung injury associated with inflammatory conditions like Sickle Cell Disease, cigarette smoking and flu. To achieve this goal, my lab uses multiscale-integrative-physiological approaches such as intravital microscopy of intact lung and other organs in mice, human blood in ex vivo microfluidic platforms, cell/tissue-specific conditional knock out mice, cell-specific fluorescent reporter mice, analytical assessment of circulating extracellular vesicles (EVs), Omics, and studies with patient samples.

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