OC 61 - Inhibitors - Immune tolerance induction

Moderator(s)

• 

  Bhavya Doshi

  Assistant Professor
  Division of Hematology, Children's Hospital of Philadelphia
  Philadelphia, Pennsylvania, United States
• 

  Seung min Hahn, MD

  Assistant Professor, Pediatric Hemato-oncology
  Severance Hospital, Yonsei University College of Medicine
  Seoul, Seoul-t'ukpyolsi, Republic of Korea

Presentations:

• 14:45 – 15:00 ICT

  Factor VIII immunization results in expansion of long-lived plasma cells in mice
  

  Co-Author: Tammi L. Briscoe – Division of Hematology, Children's Hospital of Philadelphia

  Co-Author: Silvia Juarez Rojas – Division of Hematology, Children's Hospital of Philadelphia

  Presenting Author: Bhavya S. Doshi – Division of Hematology, Children's Hospital of Philadelphia
• 15:00 – 15:15 ICT

  Determinants of successful immune tolerance induction in people with severe hemophilia A
  

  Presenting Author: Ilja Oomen, MD – Department of Pediatric Hematology, Amsterdam UMC location University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands

  Co-Author: Ricardo Mesquita Camelo, MD, MBA, MSc, PhD, PostD – Department of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil

  Co-Author: Manuel Carcao – Department of Pediatrics, Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Canada

  Co-Author: Giancarlo Castaman – Department of Oncology Careggi University Hospital, Florence, Italy

  Co-Author: Kathelijn Fischer – Centre for Benign Haematology, Thrombosis and Haemostasis, Van Creveldkliniek, University Medical Centre Utrecht, Utrecht University, Utrecht, The Netherlands

  Co-Author: Frank W.G Leebeek, MD PhD – Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands

  Co-Author: David Lillicrap, MD – Molecular Hemostasis Research Group, Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada.

  Co-Author: Maria Elisa Mancuso, MD, PhD – Centre for Thrombosis and Haemorrhagic Diseases, IRCCS Humanitas Research Hospital

  Co-Author: Davide Matino – Division of Hematology & Thromboembolism, Department of Medicine, McMaster University, Ontario, Canada

  Co-Author: Matteo Di Minno – Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy

  Co-Author: Alexander Mohseny – Department of Pediatric Hematology, Leiden University Medical Center, Leiden, the Netherlands

  Co-Author: Johannes Oldenburg, MD – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine

  Co-Author: Suely M. Rezende, MD, PhD – Universidade Federal de Minas Gerais

  Co-Author: Georges-Etienne Rivard – Department of Pediatrics, Division of Hematology-Oncology, Montréal University, CHU Sainte-Justine, Montréal, Québec, Canada

  Co-Author: Natalia Rydz – Department of Medicine, Division of Hematology, University of Calgary, Calgary, Alberta, Canada

  Co-Author: Saskia E.M. Schols – Department of Hematology, Radboud university medical center, Nijmegen, The Netherlands

  Co-Author: Jan Voorberg – Department of Molecular Hematology, Sanquin Research and Landsteiner Laboratory, Amsterdam, the Netherlands

  Co-Author: Karin Fijnvandraat – Emma Kinderziekenhuis/AMC, University of Amsterdam, Netherlands

  Co-Author: Samantha C. Gouw, MD PhD – Department of Pediatric Hematology, Emma Children’s Hospital, Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands

  Co-Author: Jeroen Eikenboom – Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands
• 15:15 – 15:30 ICT

  More cost-effective of intermediate-dose immune tolerance induction regimen for severe hemophilia A children with high-titer inhibitors: the interim report of a randomized multicenter clinical trial
  

  Presenting Author: Zhengping Li, Medical Doctor in progress – zhengp_li@163.com

  Co-Author: Man-Chiu Poon – University of Calgary

  Co-Author: Runhui Wu, PhD, MD – Department of Hematology, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, 100045, China
• 15:30 – 15:45 ICT

  Immune tolerance induction (ITI) strategies in haemophilia A patients with inhibitors – Interim analysis from the MOTIVATE study
  

  Presenting Author: Carmen Escuriola Ettingshausen, MD – HZRM Hämophilie Zentrum Rhein Main

  Co-Author: Robert F. Sidonio, Jr., MD, M.Sc. – Emory University
• 15:45 – 16:00 ICT

  Immune tolerance induction in patients with hemophilia A and high-titer inhibitors with emicizumab prophylaxis
  

  Co-Author: Carolina Costa-Lima – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Vanessa B Faiotto – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Jéssica O. Frade-Guanaes – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Ana P. Francisco – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Nívia M. Foschi – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Andrea L. A. Sambo – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Mariana M. T. Hosokawa – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Valdirene C. Stahl – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Samuel S Medina – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Marina P. Collela – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Silmara A. De Lima-Montalvão – Hemocentro UNICAMP, University of Campinas, Campinas, SP, Brazil

  Co-Author: Gabriela G. Yamaguti-Hayakawa – Hemocentro Unicamp, Universidade de Campinas (Unicamp), Campinas, SP, Brasil

  Presenting Author: Margareth C. Ozelo, MD, PhD – Hemocentro UNICAMP, Department of Internal Medicine, School of Medical Sciences, University of Campinas