OC 64 - Novel mechanisms and therapeutic approaches in atherothrombosis

Moderator(s)

• 

  Riitta Lassila, MD, PhD

  Professor of Coagulation Medicine
  Department of Hematology, Coagulation Disorders Unit, and Research Program Unit in Systems Oncology Oncosys, Medical Faculty, University of Helsinki, Finland
  Helsinki, Uusimaa, Finland
• 

  Young-Hoon Jeong, MD, PhD

  Professor
  Chung-Ang University Gwangmyeong Hospital
  Gwangmyeong, Kyonggi-do, Republic of Korea

Presentations:

• 14:45 – 15:00 ICT

  First-in-class human antibodies targeting protein disulfide isomerase effectively attenuate arterial thrombosis, vascular inflammation, and ischemic stroke in mice
  

  Presenting Author: Jaehyung Cho, Dr. – Washington University School of Medicine

  Co-Author: Gavriel Brown – Washington University School of Medicine

  Co-Author: Jingu Lee – Washington University School of Medicine

  Co-Author: Jae-sung Kim – Washington University School of Medicine

  Co-Author: Nam-Kyung Lee – KRIBB

  Co-Author: Jinzhi Wang – Washington University School of Medicine

  Co-Author: jeong-Ki Min – MabTics

  Co-Author: Jin-Moo Lee – Washington University school of Medicine
• 15:00 – 15:15 ICT

  Platelet releasate attenuates ischemic damage in acute myocardial infarction in mice
  

  Presenting Author: Yong Li, PhD – School of Physiology, Pharmacology & Neuroscience, University of Bristol

  Co-Author: Nathalie Tarassova – University of Bristol

  Co-Author: Samantha Mason – University of Cambridge

  Co-Author: Ingeborg Hers – University of Bristol

  Co-Author: Tim Chico – University of Sheffield

  Co-Author: Cedric Ghevaert – University of Cambridge

  Co-Author: Alastair Poole – University of Bristol
• 15:15 – 15:30 ICT

  Red blood cell-derived semaphorin 7A promotes arterial thrombosis via platelet integrin αIIb
  

  Presenting Author: Chaojun Tang, PhD – Soochow University

  Co-Author: Lijie Ren – Soochow University

  Co-Author: Anni Wang – Soochow University

  Co-Author: Chu Liu – Soochow University

  Co-Author: Qiongyu Lu – Soochow University

  Co-Author: Fengchan Li – Soochow University

  Co-Author: Li Zhu – Soochow University
• 15:30 – 15:45 ICT

  Key roles of platelet Rubicon in thrombosis and hemorrhage during ischemia-reperfusion injury
  

  Presenting Author: Hu Hu, PhD – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.

  Co-Author: Jingke Li – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.

  Co-Author: Xiaoyan Chen – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.

  Co-Author: Li Li – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.

  Co-Author: Fan Bu – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.

  Co-Author: Xin Deng – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.

  Co-Author: Yilin Sheng – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.

  Co-Author: Qiming Sun – Department of Biochemistry and Molecular Biology, Zhejiang University School of Medicine, Hangzhou, China
• 15:45 – 16:00 ICT

  Antithrombotic therapy and its discontinuation in patients with cancer during their last phase of life: a primary care cohort study from the SERENITY consortium
  

  Presenting Author: Denise Abbel – Department of Internal Medicine – section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands

  Co-Author: Emmy M. Trinks-Roerdink – Department of General Practice & Nursing Science, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands

  Co-Author: Suzanne C. Cannegieter – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

  Co-Author: Jamilla Goedegebuur, MD – Leiden University Medical Center

  Co-Author: Jacobijn Gussekloo – Department of Internal Medicine – section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands

  Co-Author: Erik Klok, MD, PhD, FESC – Leiden University Medical Center

  Co-Author: Simon Mooijaart – Department of Internal Medicine – section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands

  Co-Author: Simon I.R. Noble – Marie Curie Palliative Care Research Centre, Cardiff University, Cardiff, United Kingdom.

  Co-Author: Johanneke Portielje – Department of Internal Medicine, section of Medical Oncology, Leiden University Medical Center

  Co-Author: Stella Trompet – Department of Internal Medicine – section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands

  Co-Author: Geert-Jan Geersing – Department of General Practice & Nursing Science, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands

  Co-Author: Carline van den Dries – Department of General Practice & Nursing Science, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands