OC 68 - Modulating platelet behavior

Moderator(s)

• 

  Sofia Ramström, PhD, Associate Professor

  Associate professor
  School of Medical Sciences, Cardiovascular Research Centre Örebro University, Sweden
  Örebro, Orebro Lan, Sweden
• 

  Daniëlle Coenen, MD, PhD

  Postdoctoral Scholar
  Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
  Lexington, Kentucky, United States

Presentations:

• 14:45 – 15:00 ICT

  Discovery of piezo1 as a mediator of mechanotransduction in platelets
  

  Co-Author: Arif s/o Abdul Jabbar – Cambridge University

  Co-Author: Suman Guntupalli – Cleveland Clinic

  Co-Author: Rohan Bhandari – Cleveland Clinic

  Co-Author: Anu Aggarwal – Cleveland Clinic

  Co-Author: Matthew Godwin – Cleveland Clinic

  Co-Author: Mariya Ali – Cleveland Clinic

  Co-Author: Edelyn Huijun Park – Cleveland Clinic

  Co-Author: Reina Samuel – Cleveland Clinic

  Presenting Author: Scott J. Cameron, PhD, MD – Cleveland Clinic
• 15:00 – 15:15 ICT

  SLFN14 deletion causes macrothrombocytopenia and thrombus instability by dysregulating ubiquitination and degradation pathways in platelets and megakaryocytes.
  

  Presenting Author: Neil V. Morgan, PhD – University of Birmingham

  Co-Author: Xenia Sawkulycz – University of Birmingham

  Co-Author: Rachel Stapley – University of Birmingham

  Co-Author: Lourdes Garcia Quintanilla – University of Birmingham

  Co-Author: Amna Ahmed – University of Birmingham

  Co-Author: Elizabeth Haining – University of Birmingham

  Co-Author: Nayandeep Kaur – University of Birmingham

  Co-Author: Andrea Bacon – University of Birmingham

  Co-Author: Dean Kavanagh – University of Birmingham

  Co-Author: Natalie Poulter – University of Birmingham

  Co-Author: Julie Rayes, PhD – University of Birmingham

  Co-Author: Steve Thomas – University of Birmingham
• 15:15 – 15:30 ICT

  FLI-1 variants reduce TALIN1 expression in human megakaryocytes and platelets
  

  Presenting Author: ELISA GABINAUD, Master's degree – C2VN

  Co-Author: Laurent Hannouche – C2VN

  Co-Author: Mathilde Veneziano Broccia – C2VN

  Co-Author: Timothée Bigot – C2VN

  Co-Author: Elisa Andersen – C2VN

  Co-Author: Paul Saultier – hospital APHM

  Co-Author: Manal IBRAHIM – Biologic Hematology, hospital APHM, Marseille

  Co-Author: Justine SUFFIT – C2VN

  Co-Author: Anne Bauters – CHU Lille, Service d'Hemostase et Transfusion - Lille FRANCE

  Co-Author: Anne Vincenot – CHU Paris Robert Debré, Paris, France

  Co-Author: Marie-Christine ALESSI – Aix Marseille Univ, Inserm 1263, inrae 1260, C2VN, APHM

  Co-Author: Marjorie POGGI – AMU
• 15:30 – 15:45 ICT

  Transmembrane TMX1 counterbalances the effect of ERp46 to inhibit platelet activation
  

  Presenting Author: Zhenzhen Zhao, MD – Soochow Universtiy

  Co-Author: yixin cheng – National Clinical Research Center for Hematologic Diseases,Soochow University

  Co-Author: meinan peng – Soochow University

  Co-Author: yuxin zhang – National Clinical Research Center for Hematologic Diseases, Cyrus Tang Medical Institute，Soochow University

  Co-Author: Shuo Liu – Soochow University

  Co-Author: Yaowei Sun – Soochow Universtiy

  Co-Author: Yue han – National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, First Affiliated Hospital of Soochow University

  Co-Author: Depei Wu – The First Affiliated Hospital of Soochow University

  Co-Author: Aizhen Yang, PhD – The Cyrus Tang Hematology Center, Soochow University
• 15:45 – 16:00 ICT

  Platelet Drp1 phosphorylation is controlled by a dual phosphorylation pathway requiring dense granule release: Implications for evaluating antiplatelet therapy
  

  Co-Author: David A. Barrios – PlateletDiagnostics, LLC

  Co-Author: Secil Koseoglu – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center

  Co-Author: Shihui Guo – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center

  Co-Author: Sabrina Zerbey – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center

  Co-Author: Matthew Powers – PlateletDiagnostics

  Co-Author: Arielle Urman – Beth Israel Deaconess Medical Center

  Co-Author: Somal Khan – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center

  Co-Author: Dominick Svrcek – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center

  Co-Author: Haley Clark – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center

  Co-Author: Rushad Patell, MBBS – Beth Israel Deaconess Medical Center

  Co-Author: Jeffrey I. Zwicker, MD – Hematology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA

  Presenting Author: Robert Flaumenhaft, MD, PhD – BIDMC/Harvard Medical School