Bryan R. Bouwens, MSc

PhD candidate
CARIM - department of biochemistry - Maastricht university
Maastricht, Limburg, Netherlands

Bryan Bouwens, MSc. PhD Candidate at Maastricht University (NL), Cardiovascular Research Institute Maastricht (CARIM), Department of Biochemistry.

Bachelor of science in biomedical science
Master of science in genetics and genomics

The focus of my work has been Tissue Factor Pathway Inhibitor (TFPI) and Neutrophils. More specifically, how an enzyme (PAD4) involved in NETosis can induce a post-translational modification called citrullination in TFPI, and how that can adverserly affect the function of the natural anticoagulant role of TPFI.

Presentation(s):

• OC 76.4 - Citrullination of TFPI impairs its natural anticoagulant activity towards factors Xa, VIIa and tissue factor, and reduces binding of its cofactor protein S.

  Wednesday, June 26, 2024
  11:00 – 11:15 ICT