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Keiko Shinozawa, PhD

Assistant Professor
Department of Laboratory Medicine, Tokyo Medical University/Japan
Shinjuku-ku, Tokyo, Japan

Keiko Shinozawa, Ph.D.
Assistant Professor, Department of Laboratory Medicine, Tokyo Medical University

EDUCATION:
1984-1988 Tokyo University of Science, Faculty of Science, Department of Chemistry.
1988-1997 Tokyo Medical University, Department of Clinical Pathology, majored in Coagulation Disorders.

PROFESSIONAL TRAINING and EMPLOYMENT:
1997-2007 Research Resident, Department of Laboratory Medicine, Tokyo Medical University.
2007-2020 Assistant Professor, Department of Molecular Genetics of Coagulation Disorders, Tokyo Medical University.
2020- Assistant Professor, Department of Laboratory Medicine, Tokyo Medical University.

MEMBERSHIPS:
International Society on Thrombosis and Haemostasis.
The Japanese Society on Thrombosis and Hemostasis.
Japanese Society of Laboratory Medicine.

MAJOR RESEARCH INTERESTS:
Coagulation Disorders, Hemophilia, Carrier, Molecular Genetics.

MAIN PUBLICATIONS
1. Shinozawa K, et.al. Trisomy X conferring moderate hemophilia A by extremely skewed X-chromosome inactivation. Res Pract Thromb Haemost. 17;7(7):102233. 2023.
2. Yamaguchi T, Shinozawa K, et.al. In vitro validation of chromogenic substrate assay for evaluation of surrogate FVIII-activity of emicizumab. Thromb Res. 222:131-139.2023.
3. Miyashita R, Shinozawa K, et.al. Prolonged α-thrombin-related activation and delayed active protein C-associated degradation confer mild phenotype in a patient with severe hemophilia A with F8 p.H118R. Int J Hematol. 16(4):489-499. 2022.
4. Shinozawa K, et.al. Genetic analysis of carrier status in female members of Japanese hemophilia families. J Thromb Haemost. 19(6):1493-1505. 2021.
5. Shinozawa K, Yada K, et.al. Spectrum of F8 Genotype and Genetic Impact on Inhibitor Development in Patients with Hemophilia A from Multicenter Cohort Studies (J-HIS) in Japan. Thromb Haemost. 121(5):603-615. 2021.
6. Tamura A, Shinozawa K, et.al. Early elevation of factor IX level in japanese brothers with Haemophilia B Leyden who are carrying c. -35 g > a mutations in the promoter region of F9. Haemophilia. 27(4):e510-e512. 2021.
7. Nogami K, Shinozawa K, et.al. Novel FV mutation (W1920R, FV Nara) associated with serious deep vein thrombosis and more potent APC resistance relative to FV Leiden. Blood. 123(15):2420-8. 2014.

Presentation(s):