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CME Evaluation

Oral Communication Session

Venous Thromboembolism

Session: VTE long term complications

OC 74.3 - Development of a new disease-specific health-related quality of life questionnaire for deep vein thrombosis

Wednesday, June 26, 2024
10:45 – 11:00 ICT
Room: 110 A-C
Background: A disease-specific health-related quality of life (HRQoL) questionnaire for DVT patients developed according to the current guidelines does not exist.

Aims: To develop a new disease-specific HRQoL questionnaire for DVT in accordance with state-of-the-art recommendations.

Methods: The questionnaire development followed a standardized phase I-IV development, of which results from phase III are presented in this abstract. Results from the previous phases were used to create a 52-item questionnaire. DVT patients were asked to complete the questionnaire. In phase III a total of 128 patients from Norway, Canada and The Netherlands completed this questionnaire. Phase III was conducted in two parts. First 33 patients completed the questionnaire to identify practical and linguistic clarity issues, whereas 95 patients completed the questionnaire in the second part. A preliminary psychometric analysis as well as correlation-based methods, Cronbach's α, and intra-class correlation coefficient were assessed for item reduction.

Results: The first part of phase III resulted in minor language adjustments, the removal of two items and one item was divided in to two, resulting in a 51-item questionnaire. Floor and ceiling effects, as well as the above-mentioned methods were used to identify the relevant items for HRQoL of DVT patients. The final questionnaire consists of 23 items that fulfilled the criteria for item retention (table 1)

Conclusion(s): We have developed a HRQoL questionnaire for DVT according to the latest guidelines for questionnaire development. The questionnaire is now ready for psychometric validation in different languages.