PB0378 - Incidence of venous thromboembolic disease in covid-19 patients during hospitalization and within 90 days after discharge

Background: COVID-19 infection can lead to systemic activation of coagulation and thrombotic complications.

Aims: We sought to determine the incidence and identify factors associated with the development of VTE in hospitalized COVID-19 patients and within 90 days of discharge

Methods: An observational, descriptive and single-center study was conducted at the Hospital de Clínicas de Montevideo during the period March-July 2021. Data were obtained through electronic medical records and telephone follow-up after discharge for three months in order to evaluate the presence of VTE.

Results: We included 120 hospitalized patients with COVID-19 followed during hospitalization and up to 3 months after discharge. Mortality was 34/120 (28.3%), of which three died from PE (including one pregnant woman).
During hospitalization, an incidence of VTE of 7/120 (5.8%) was observed. In all cases, the form of presentation was PE.
Regarding the population followed after discharge 73/86 (84.8%), the incidence of VTE was 1/73 (1.4%). The form of presentation was DVT/PE.
There were no statistically significant differences between the group of patients with VTE vs non-VTE with respect to demographic, clinical or paraclinical variables or mortality. See tables 1 and 2. This could be explained by the number of patients included in our work.

Conclusion(s): The present study showed a low incidence of venous thrombotic complications in hospitalized patients of 5.8%, as well as after hospital discharge with an incidence of 1.4%, results similar to international reports of the same period in which the advance in the knowledge of the disease and the universalization of therapeutic management in this group of patients was probably already evident.