OC 59 - Mechanical forces and thrombus dynamics

Moderator(s)

• 

  Robert Ariens, PhD

  Professor of Vascular Biologu
  University of Leeds
  Leeds, United Kingdom
• 

  Alexandra Raska

  PhD student
  Semmelweis University Department of Biochemistry and Molecular Biology
  Budapest, Budapest, Hungary

Presentations:

• 09:30 – 09:45 ICT

  Presence of red blood cells promotes tension-dependent cleavage of von Willebrand factor in whole blood under high shear
  

  Co-Author: Rukiye Tuna – Florida State University

  Co-Author: Alice Liu – Washington University in St. Louis

  Co-Author: David Bark, Jr., PhD – Washington University in St. Louis

  Presenting Author: Leo Liu – Florida State University
• 09:45 – 10:00 ICT

  Histidine Residues in the Von Willebrand Factor D4 Domain Alter VWF Function in Response to Shear Stress
  

  Presenting Author: Golzar Mobayen, MSc – Imperial College London

  Co-Author: Yi Liu – University of Massachusetts

  Co-Author: X.Frank Zhang – University of Massachusetts

  Co-Author: Tom McKinnon – Imperial College London
• 10:00 – 10:15 ICT

  A Novel Mechanism Mediated by Allosteric Disulfide Bonds Fine-Tunes Thrombus Formation
  

  Presenting Author: Keyu Lv, phD – Huazhong University of Science and Technology

  Co-Author: Shuai Chen – Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology

  Co-Author: Xulin Xu – Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology

  Co-Author: Joyce Chiu – The Centenary Institute, University of Sydney

  Co-Author: Haoqing J. Wang – School of Biomedical Engineering, Faculty of Engineering, The University of Sydney

  Co-Author: Yunyun Han – Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology

  Co-Author: Xiaodan Yang – Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology

  Co-Author: Sheryl R Bowley – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School

  Co-Author: Zhaoming Tang, MD – Department of Clinical Laboratory, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

  Co-Author: Ning Tang, MPH – Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology

  Co-Author: Aizhen Yang, PhD – The Cyrus Tang Hematology Center, Soochow University

  Co-Author: Yi Wu, MD, PhD – Soochow University

  Co-Author: Lining A. Ju, PhD – University of Sydney

  Co-Author: Alvin H. Schmaier – Department of Medicine, University Hospitals Cleveland Medical Center and Case Western Reserve University

  Co-Author: Philip Hogg, BSc(Hon), PhD – University of Technology Sydney and Centenary Institute

  Co-Author: Chao Fang, PhD – Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology
• 10:15 – 10:30 ICT

  A Microfluidic Approach in TTP Highlights the Need to Normalise ADAMTS13 Activity Levels in Clinical Remission in iTTP and the Effect of Different Treatments on Disease Activity in cTTP
  

  Presenting Author: Adela Constantinescu-Bercu, BSc MPhil PhD – Imperial College London

  Co-Author: Rens de Groot – University College London

  Co-Author: Bertina Dragunaite – University College London

  Co-Author: Sabina McCann – Health Services Laboratories, UK

  Co-Author: Raphael Sivera – University College London

  Co-Author: Karen Vanhoorelbeke – Laboratory for Thrombosis Research, IRF Life Sciences, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium

  Co-Author: Marie Scully – University College London
• 10:30 – 10:45 ICT

  Rupture Mechanics of Blood Clots: Influence of Fibrin Structure on the Rupture Resistance
  

  Presenting Author: Ranjini Ramanujam – Rutgers University

  Co-Author: Farkhad Maksudov – University of Massachusetts Lowell

  Co-Author: Rebecca A. Risman – Rutgers University

  Co-Author: Rustem I. Litvinov – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

  Co-Author: John W. Weisel – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA

  Co-Author: John bassani – university of Pennsylvania

  Co-Author: Valeri Barsegov – University of Massachusetts Lowell

  Co-Author: Prashant K. Purohit – university of Pennsylvania

  Co-Author: Valerie Tutwiler – Rutgers University