OC 10 - Organic compounds in thromboinflammation

Moderator(s)

• 

  Lining Ju, PhD

  University of Sydney, Australia
• 

  Dianne van der Wal, PhD

  Researcher
  ANZAC Research Institute
  Sydney, New South Wales, Australia

Presentations:

• 13:00 – 13:15 ICT

  Alterations in tryptophan metabolism in mice and humans infected with SARS-CoV-2 contribute to a prothrombotic milieu
  

  Presenting Author: Saravanan Subramaniam, M.Pharm., PhD – Department of Pharmaceutical Sciences, School of Pharmacy, MCPHS University, Boston, USA

  Co-Author: Marc Arthur Napoleon – Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Saran Lotfollahzadeh – Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Mohamed Hassan Kamal – Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Helena Kurniawan – Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Murad Elsadawi – Renal Section, Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Florian Dhouam – Department of Microbiology, National Institute of Emerging Infectious Diseases, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Norman Lee – Department of Microbiology, National Institute of Emerging Infectious Diseases, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Markus Bosmann – Pulmonary Center, Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA

  Co-Author: Stephen Whelan – Chemical Instrumentation Center, Department of Chemistry, Boston University, Boston, MA, 02118, USA

  Co-Author: Eric Burk – Department of Pharmacology and Toxicology, Massachusetts College of Pharmacy and Health Sciences, Boston, MA 02115, USA

  Co-Author: Grace Zhao – Department of Pharmacology and Toxicology, Massachusetts College of Pharmacy and Health Sciences, Boston, MA 02115, USA

  Co-Author: Vijay Kolachalama – Department of Biostatistics, School of Public Health, Boston University, MA, 02118, USA Computational Medicine, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Katya Ravid – Department of Medicine and Whitaker Cardiovascular Institute, Chobanian & Avedisian School of Medicine, Boston University, Boston, MA 02118, USA

  Co-Author: Vipul Chitalia – Center of Cross-Organ Vascular Pathology (COVP), Department of Medicine, Chobanian & Avedisian School of Medicine, Boston University Medical Center, Boston, MA 02118, USA
• 13:15 – 13:30 ICT

  A novel role for itaconate in trained immunity and myeloid cell-mediated hypercoagulability
  

  Presenting Author: Aisling M. Rehill, BEng MSc PhD – Irish Centre for Vascular Biology,School of Pharmacy and Biomolecular Sciences,RCSI University of Medicine and Health Sciences, Dublin, Ireland

  Co-Author: Gemma Leon, MSc PhD – Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland

  Co-Author: Tristram AJ Ryan – School of Biochemistry and Immunology, Trinity College Dublin, Ireland

  Co-Author: Anna E. Ledwith – 3School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.

  Co-Author: Emily A. Day – 3School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland.

  Co-Author: Corrina McMahon – 2National Children’s Research Centre, Our Lady’s Children’s Hospital Crumlin, Dublin, Ireland

  Co-Author: James S. O'Donnell – Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland.

  Co-Author: Annie M. Curtis – School of Pharmacy and Biomolecular Sciences, RCSI University of Medicine and Health Sciences, Dublin, Ireland

  Co-Author: Luke AJ O'Neill – School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland

  Co-Author: Frederick J. Sheedy – School of Biochemistry and Immunology, Trinity College Dublin, Dublin, Ireland

  Co-Author: Roger J.S. Preston – Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland.
• 13:30 – 13:45 ICT

  Tissue factor and interferon-alpha receptor-1 interaction constitutes a thrombo-inflammatory switch
  

  Co-Author: Jayakumar Manoharan, M.Tech – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany

  Co-Author: Rajiv Rana – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany

  Co-Author: Ahmed Elwakiel – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany

  Co-Author: Georg Kuenze – Institute for Drug Discovery, Leipzig University Medical School, Leipzig, Germany

  Presenting Author: Berend Isermann, Prof. Dr. med. – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany
• 13:45 – 14:00 ICT

  Bioengineered Vascular Model of Foam Cell Formation
  

  Presenting Author: Ying Zhou – baker heart and diabetes institute

  Co-Author: Nadia Chandra Sekar – RMIT university

  Co-Author: Peter Thurgood – RMIT university

  Co-Author: Scott Needham – Leading Technology Group

  Co-Author: Karlheinz Peter – Baker Heart and Diabetes Institute

  Co-Author: Khashayar Khoshmanesh – RMIT university

  Co-Author: Sara Baratchi – Baker institute
• 14:00 – 14:15 ICT

  Protein Disulfide Isomerase Links Sulfenylation to a Prothrombotic Phenotype in Glutathione Peroxidase 3-Deficient Oxidative Stress Mice
  

  Presenting Author: Moua Yang, PhD – Beth Israel Deaconess Medical Center

  Co-Author: Anika Patel – Beth Israel Deaconess Medical Center

  Co-Author: Christina Scartelli – Beth Israel Deaconess Medical Center

  Co-Author: Kate S. Carroll – UF Scripps Biomedical Research

  Co-Author: Diane E. Handy – Brigham and Women's Hospital

  Co-Author: Joseph Loscalzo – Brigham and Women's Hospital

  Co-Author: Nicola Pozzi – Saint Louis University School of Medicine

  Co-Author: Robert Flaumenhaft, MD, PhD – BIDMC/Harvard Medical School