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  • Saturday, Jun 22nd
    13:00 – 13:15 ICT
    OC 09.1 - A Common Variant in GRK5 Reveals Novel Targets for its Regulation of Platelet Function
    Room: 208 A-D
    Co-Author: Yanki Yarman – Thomas Jefferson University
    Co-Author: Xuefei Zhao – Thomas Jefferson University
    Co-Author: Matthew Cooper – Thomas Jefferson University
    Co-Author: Hannah Thomson – Thomas Jefferson University
    Co-Author: Steven McKenzie – Thomas Jefferson University
    Co-Author: Jeffrey Benovic – Thomas Jefferson University
    Presenting Author: Peisong Ma, PhD – Thomas Jefferson University
    Platelets and Megakaryocytes
  • Saturday, Jun 22nd
    13:15 – 13:30 ICT
    OC 09.2 - Blocking thrombin-mediated cleavage of platelet glycoprotein V to treat hemorrhagic complications.
    Room: 208 A-D
    Presenting Author: Katarzyna Derszniak, PhD – 1. Institute of Experimental Biomedicine, University Hospital Würzburg, Germany 2. Rudolf Virchow Center for Integrative and Translational Bioimaging, Julius-Maximilians University of Würzburg, Germany
    Co-Author: Patricia Öftering – Institute of Experimental Biomedicine, University Hospital Würzburg, Germany
    Co-Author: David Stegner – Institute for Experimental Biomedicine, University Hospital Würzburg
    Co-Author: Bernhard Nieswandt – University Hospital Würzburg
    Co-Author: Sarah Beck – Institute of Experimental Biomedicine, University Hospital Würzburg, Germany
    Platelets and Megakaryocytes
  • Saturday, Jun 22nd
    13:30 – 13:45 ICT
    OC 09.3 - CD36-dependent metabolic rewiring and mitochondrial dysfunction in platelets in response to hyperlipidaemia – new mechanisms of platelet hyperactivity
    Room: 208 A-D
    Presenting Author: Lih T. Cheah, PhD – University of Leeds
    Co-Author: Jawad Khalil – University of Leeds
    Co-Author: Matthew S. Hindle – Leeds Beckett University
    Co-Author: Reem Alotaibi – University of Leeds
    Co-Author: Mark Kearney – University of Leeds
    Co-Author: Khalid M. Naseem – University of Leeds
    Platelets and Megakaryocytes
  • Saturday, Jun 22nd
    13:45 – 14:00 ICT
    OC 09.4 - Notch1 regulates hepatic thrombopoietin production
    Room: 208 A-D
    Co-Author: Yueyue Sun – Xuzhou Medical University
    Co-Author: Huan Tong – Xuzhou Medical University
    Co-Author: Xiang Chu – Xuzhou Medical University
    Co-Author: Lingyu Zeng – Xuzhou Medical University
    Co-Author: Kailin Xu – Xuzhou Medical University
    Presenting Author: Jianlin Qiao, PhD – Xuzhou Medical University
    Platelets and Megakaryocytes
  • Saturday, Jun 22nd
    14:00 – 14:15 ICT
    OC 09.5 - CLEC-2 mediates ferric chloride-induced platelet activation and attenuates ferroptosis in endothelial cells.
    Room: 208 A-D
    Presenting Author: Nagaharu Tsukiji, PhD – Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi
    Co-Author: Ryohei Yokomori – Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi
    Co-Author: Kazuho Takusagawa – University of Yamanashi Hospital
    Co-Author: Toshiaki Shirai, PhD – Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi
    Co-Author: Saori Oishi – Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi
    Co-Author: Tomoyuki Sasaki – Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi
    Co-Author: Katsuhiro Takano – Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi
    Co-Author: Katsue Suzuki-Inoue, MD, PhD – Department of Clinical and Laboratory Medicine, Faculty of Medicine, University of Yamanashi
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    08:00 – 08:20 ICT
    SOA 06.1 - Platelet dysfunction in myeloproliferative neoplasms
    Room: Ballroom B1
    Speaker: Chloe James, MD PhD – University of Bordeaux
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    08:25 – 08:45 ICT
    SOA 06.2 - Megakaryopoiesis in autoimmune environments
    Room: Ballroom B1
    Speaker: Tamam Bakchoul, Professor MD – Center for Clinical and Experimental Transfusion Medicine, University Hospital of Tuebingen
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    08:50 – 09:10 ICT
    SOA 06.3 - Bone marrow environment and megakaryopoiesis
    Room: Ballroom B1
    Speaker: Wen Zhou, PhD – Cancer Research Institute,Central South University
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    09:30 – 09:45 ICT
    OC 18.1 - CXCL12 abundant reticular (CAR) cells spatially regulate platelet production in the bone marrow
    Room: 211 A-D
    Presenting Author: Margret Droste, M.sc. – University Hospital Würzburg, Institute of Experimental Biomedicine I
    Co-Author: Kristina Mott – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany
    Co-Author: Harald Schulze – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    09:45 – 10:00 ICT
    OC 18.2 - Differentiation route determines the functional outputs of adult megakaryopoiesis
    Room: 211 A-D
    Presenting Author: Yueying Li, MD – Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation
    Co-Author: Jing-jing Li – Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Jingkun Liu – Beijing Institute of Genomics, Chinese Academy of Sciences (CAS)
    Co-Author: Yunqian Evelyn Li – Shanghai Institute of Biochemistry and Cell Biology, CAS
    Co-Author: Lin Veronica Chen – Shanghai Institute of Biochemistry and Cell Biology, CAS
    Co-Author: Hui Cheng – Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Tao Cheng – Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Qian-fei Wang – Beijing Institute of Genomics, Chinese Academy of Sciences (CAS)
    Co-Author: Bo O. Zhou – Shanghai Institute of Biochemistry and Cell Biology, CAS
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    10:00 – 10:15 ICT
    OC 18.3 - New profile of immune embryonic-like megakaryocytes: Role on RUNX1
    Room: 211 A-D
    Presenting Author: Cecilia P. Marin Oyarzun, PhD – Inserm UMR1287, Gustave Roussy, Université Paris Saclay, Équipe labelisée LNCC, Villejuif, France
    Co-Author: Brahim Arkoun – Inserm UMR1287, Gustave Roussy, Université Paris Saclay, Équipe labelisée LNCC, Villejuif, France
    Co-Author: Nathalie Balayn – Inserm UMR1287, Gustave Roussy, Université Paris Saclay, Équipe labelisée LNCC, Villejuif, France
    Co-Author: Vithuzane Selvarasa – Sorbonne Université, Paris, France
    Co-Author: Ana Glembtosky – Universidad de Buenos Aires, Facultad de Medicina, Instituto de Investigaciones Médicas "Alfredo Lanari", IDIM UBA-CONICET, Departamento de Hematologia Investigacion, Buenos Aires, Argentina
    Co-Author: Marine Aglave – Gustave Roussy, Plateforme de Bio-informatique, Villejuif, France
    Co-Author: William Vainchenker – Inserm UMR1287, Gustave Roussy, Université Paris Saclay, Équipe labelisée LNCC, Villejuif, France
    Co-Author: Isabelle Plo – Inserm UMR1287, Gustave Roussy, Université Paris Saclay, Équipe labelisée LNCC, Villejuif, France
    Co-Author: Paula Heller – Universidad de Buenos Aires, Facultad de Medicina, Instituto de Investigaciones Médicas "Alfredo Lanari", IDIM UBA-CONICET, Departamento de Hematologia Investigacion, Buenos Aires, Argentina
    Co-Author: Hana Raslova – INSERM U1287, Gustave Roussy, Université Paris Saclay, Villejuif, France
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    10:15 – 10:30 ICT
    OC 18.4 - Plasmacytoid dendritic cells regulate tissue homeostasis of megakaryocytes
    Room: 211 A-D
    Presenting Author: Florian Gaertner, MD, PhD – LMU Klinikum
    Co-Author: Hellen Ishikawa-Ankerhold – Department of Medicine I, LMU University Hospital, LMU Munich
    Co-Author: Susanne Stutte – Institute of Cardiovascular Physiology and Pathophysiology, Biomedical Center, LMU Munich, Planegg-Martinsried, Germany
    Co-Author: Wenwen Fu – Department of Medicine I, University Hospital, LMU Munich
    Co-Author: Jutta Weitz – Department of Medicine I, University Hospital, LMU Munich
    Co-Author: Anne Dueck – Institut für Pharmakologie und Toxikologie, Technische Universität München (TUM), Munich, Germany
    Co-Author: Bhavishya Nelakuditi – Department of Medicine I, University Hospital, LMU Munich
    Co-Author: Valeria Fumagalli – Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University
    Co-Author: Kami Pekayvaz – Department of Medicine I, University Hospital, LMU Munich
    Co-Author: Zhe Zhang – Department of Medicine I, University Hospital, LMU Munich
    Co-Author: Alejandro Martinez Navarro – Department of Medicine I, University Hospital, LMU Munich
    Co-Author: Konstantin Stark – Department of Medicine I, University Hospital, LMU Munich
    Co-Author: Stefan Engelhardt – Institut für Pharmakologie und Toxikologie, Technische Universität München (TUM), Munich, Germany
    Co-Author: Robert Hauschild – Institute of Science and Technology Austria (ISTA)
    Co-Author: Martina Rudelius – Institute of Pathology, Ludwig-Maximilians-University Munich
    Co-Author: Saskia von Stillfried – Institute of Pathology, RWTH Aachen University Hospital
    Co-Author: Peter Boor – Institute of Pathology, RWTH Aachen University Hospital
    Co-Author: Matteo Iannacone – Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute and Vita-Salute San Raffaele University
    Co-Author: Matthias Heinig – Institute of Computational Biology, Deutsches Forschungszentrum für Gesundheit und Umwelt, Helmholtz Zentrum München and Department of Informatics, Technical University of Munich
    Co-Author: Steffen Massberg – Department of Medicine I, LMU University Hospital, LMU Munich
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    10:30 – 10:45 ICT
    OC 18.5 - G6PD controls thrombopoiesis by monitoring TMOD3-regulated actin reorganization
    Room: 211 A-D
    Presenting Author: Min Xin, PhD – Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Co-Author: Chihao Zhang – Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Co-Author: Xuemei Fan – Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Co-Author: Yanyan Xu – Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Co-Author: Jing Dai – Department of Clinical Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    14:45 – 15:00 ICT
    OC 28.1 - Myosin light chain 6 (Myl6) interacts with kindlin-3 and is required to support integrin αIIbβ3 activation in platelets
    Room: 211 A-D
    Presenting Author: Zhen Xu, PhD – Versiti Blood Research Institute
    Co-Author: Ying Zhou – Research Technologist
    Co-Author: Hongyin Yu – Versiti Blood Research Institute
    Co-Author: Xue Chen – Shanghai Jiaotong University
    Co-Author: Yan-Qing Ma – Versiti Blood Research Institute
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    15:00 – 15:15 ICT
    OC 28.2 - Platelet β1 and β3 integrins are essential for hemostasis, arterial thrombosis and tumor metastasis
    Room: 211 A-D
    Presenting Author: Emily Janus-Bell, PhD – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Cristina Liboni – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), CNRS, SNC5055, Strasbourg, France
    Co-Author: Alexandra Yakusheva – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Vincent Mittelheisser – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), CNRS, SNC5055, Strasbourg, France
    Co-Author: Louis Bochler – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), CNRS, SNC5055, Strasbourg, France
    Co-Author: Clarisse Mouriaux – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Catherine Bourdon – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Maria Garcia-Leon – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), CNRS, SNC5055, Strasbourg, France
    Co-Author: Vincent Hyenne – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), CNRS, SNC5055, Strasbourg, France
    Co-Author: Olivier Lefebvre – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), CNRS, SNC5055, Strasbourg, France
    Co-Author: Jacky Goetz – INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), CNRS, SNC5055, Strasbourg, France
    Co-Author: Pierre H. Mangin, PhD – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, Strasbourg, France
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    15:15 – 15:30 ICT
    OC 28.3 - Direct binding of Lyn to GPIb beta transmembrane/cytoplasmic domain transmits platelet activation signal and regulates GPIb alpha–VWF binding
    Room: 211 A-D
    Presenting Author: Yaping Zhang, MS,MBA – University of Illinois at Chicago
    Co-Author: Ying Liang – University of illinois at Chicago
    Co-Author: Amir Hossein Kazemipour Ashkezari – Georgia Institute of Technology
    Co-Author: Cheng Zhu – Georgia Institute of Technology
    Co-Author: Xiaoping Du – University of illinois at Chicago
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    15:30 – 15:45 ICT
    OC 28.4 - Hippo pathway effector TAZ negatively regulates platelet activation and thrombosis by inhibiting MEK-ERK-cPLA2 pathway
    Room: 211 A-D
    Presenting Author: Xiaowen Wu, MA – School of Pharmacy, Tianjin Medical University, Tianjin, China
    Co-Author: Guanxing Pan – Department of Pharmacy, The First Affiliated Hospital of Fujian Medical University
    Co-Author: Yulong Zhang, MD – School of Pharmacy, Tianjin Medical University, Tianjin, China
    Co-Author: Zhiling Zhang – Institutes of Biomedical Sciences, Fudan University, Shanghai, China.
    Co-Author: Yifan Guo – Department of Cardiology, Tianjin Medical University General Hospital
    Co-Author: Li Li – Intensive Care Unit, The Second Hospital of Tianjin Medical University,
    Co-Author: Qingyuan Yang – School of Pharmacy, Tianjin Medical University
    Co-Author: Meng Du – School of Pharmacy, Tianjin Medical University
    Co-Author: Qian Liu – School of Pharmacy, Tianjin Medical University
    Co-Author: Yixian Wang – School of Pharmacy, Tianjin Medical University
    Co-Author: Meina Jin – School of Pharmacy, Tianjin Medical University
    Co-Author: Zhiqiang Zhao – Departement of Cardiology,The Second Hospital of Tianjin Medical University
    Co-Author: Fa-xing Yu – Institutes of Biomedical Sciences, Fudan University
    Co-Author: Shaopeng Xu – Department of Cardiology, Tianjin Medical University General Hospital
    Co-Author: Qing Yang – Department of Cardiology, Tianjin Medical University General Hospital
    Co-Author: Bing Chen – Intensive Care Unit,The Second Hospital of Tianjin Medical University
    Co-Author: Xiongwen Chen – School of Pharmacy, Tianjin Medical University
    Co-Author: Zhongren Ding – School of Pharmacy, Tianjin Medical University; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences , Fudan University; Department of Geriatrics, The Second Hospital of Tianjin Medical University
    Platelets and Megakaryocytes
  • Sunday, Jun 23rd
    15:45 – 16:00 ICT
    OC 28.5 - A novel experimental model of stable thrombosis: the anti-GPVI agent, glenzocimab, efficiently destabilizes an established thrombus
    Room: 211 A-D
    Presenting Author: Charlotte E. Fauth, Master student – EFS Alsace Grand Est, UMRS_1255
    Co-Author: Kim Ashley JOUFFROY, DVM – EFS-Alsace
    Co-Author: Alexandra Yakusheva – Université de Strasbourg, INSERM, EFS Grand Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Andréa Thevenot – Etablissement Français du Sang Grand-Est UMRS-1255
    Co-Author: Martine Jandrot-Perrus, MD., PhD. – Laboratory for Vascular Translational Science, UMR_S1148 INSERM, University Paris Cité, Hôpital Bichat, Paris, France
    Co-Author: Pierre H. Mangin, PhD – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, Strasbourg, France
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    08:00 – 08:20 ICT
    SOA 10.1 - Machine learned predictions for platelet biology
    Room: Ballroom B2
    Speaker: Dan Andrews, BSc (hons) PhD – John Curtin School of Medical Research and School of Computing, Australian National University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    08:25 – 08:45 ICT
    SOA 10.2 - AI for selecting antithrombotic treatments
    Room: Ballroom B2
    Speaker: Mark Thomas, MRCP PhD – University of Birmingham
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    08:50 – 09:10 ICT
    SOA 10.3 - Utilizing thrombectomy platelet data for machine learning-based cancer prediction in acute ischemic stroke
    Room: Ballroom B2
    Speaker: Hyo Suk Nam, MD, PhD – Department of Neurology, Yonsei University College of Medicine
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    09:30 – 09:45 ICT
    OC 38.1 - Altered platelet and megakaryocyte phenotype and enhanced platelet-macrophage interactions in liver fibrosis
    Room: 211 A-D
    Presenting Author: Martina Casari, Master´s degree – Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany
    Co-Author: Bettina Mros – Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany
    Co-Author: Olga An – Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany
    Co-Author: Dominik Siegl – Institute of Translational Immunology, University Medical Center of the Johannes Gutenberg University
    Co-Author: Lama Al Jurdi – Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany
    Co-Author: Kristina Mott – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany
    Co-Author: Harald Schulze – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany
    Co-Author: Detlef Schuppan – Institute of Translational Immunology, University Medical Center of the Johannes Gutenberg University
    Co-Author: Carsten Deppermann, PhD – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    09:45 – 10:00 ICT
    OC 38.2 - Platelet CLEC-2 protects liver function from septic injury by inducing macrophage activation
    Room: 211 A-D
    Presenting Author: Zhanli Xie, 202100300192 – Institute of Clinical Medicine Research, Affiliated Suzhou Hospital, Medical School of Nanjing University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    10:00 – 10:15 ICT
    OC 38.3 - Platelet secretion in wound healing: the essence of α-granule endocytosis, biogenesis, and release kinetics
    Room: 211 A-D
    Presenting Author: Daniëlle M. Coenen, MD, PhD – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Sidney W. Whiteheart – University of Kentucky
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    10:15 – 10:30 ICT
    OC 38.4 - Platelet PAR4 (F2RL3) plays protective role in Coxsackievirus B3 myocarditis
    Room: 211 A-D
    Presenting Author: Swati Sharma – Blood Research Center, UNC
    Co-Author: Willie Williams – UNC, Blood Research Center
    Co-Author: Aymen Zaid – UNC, Blood Research Center
    Co-Author: silvio Antonaik – Blood Research Centre, UNC
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    10:30 – 10:45 ICT
    OC 38.5 - Platelets promote hepatocellular carcinoma metastasis through releasing TGF-β1-mediated cancer cell autophagy
    Room: 211 A-D
    Presenting Author: Zhangyin Ming, MD,PhD – Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
    Co-Author: Meng Lu – Huazhong University of Science and Technology, Tongji Medical College, Wuhan, China
    Co-Author: Xue Gong – Huazhong University of Science and Technology, Tongji Medical College, Wuhan, China
    Co-Author: Yumin Zhang, MA – Huazhong University of Science and Technology, Tongji Medical College, Wuhan, China
    Co-Author: Yawei Guo – Huazhong University of Science and Technology, Tongji Medical College, Wuhan, China
    Co-Author: Xiangbin Zeng – Huazhong University of Science and Technology, Tongji Medical College, Wuhan, China
    Co-Author: Jiahui Gao – Huazhong University of Science and Technology, Tongji Medical College, Wuhan, China
    Co-Author: Qi Luo – Huazhong University of Science and Technology, Tongji Medical College, Wuhan, China
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    12:15 – 13:00 ICT
    MC 12.1 - Platelets in action (imaging)
    Room: 107B
    Speaker: Ingmar Schoen, PhD – RCSI University of Medicine and Health Sciences
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0723 - Development of a fully in vitro approach to generation of megakaryocytes and platelets from mouse embryonic stem cells
    Room: Exhibition Hall
    Co-Author: Jordan Vautrinot – University of bristol
    Co-Author: Alastair Poole – University of Bristol
    Co-Author: Cedric Ghevaert – University of Cambridge
    Co-Author: Samantha Mason – University of Cambridge
    Presenting Author: Xiaojuan Zhao – University of bristol
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0724 - SETD2 Promotes Megakaryocyte Polyploidization and Platelet Generation through Methylation of α-tubulin
    Room: Exhibition Hall
    Presenting Author: Jingkun Liu – Beijing Institute of Genomics, Chinese Academy of Sciences (CAS)
    Co-Author: Chen Lei – Beijing Institute of Genomics
    Co-Author: Kunying Chen – Beijing Institute of Genomics
    Co-Author: Yanxun Su – Beijing Institute of Genomics
    Co-Author: Yihe Chen – Beijing Institute of Genomics
    Co-Author: Ying Lei – Beijing Institute of Genomics
    Co-Author: Jia Si – Beijing Institute of Genomics
    Co-Author: Jie Zhang – Beijing Institute of Genomics
    Co-Author: Zhaojun Zhang – Beijing Institute of Genomics
    Co-Author: Weiguo Zou – CAS Center for Excellence in Molecular Cell Science
    Co-Author: Xiaohui Zhang – Peking University People’s Hospital
    Co-Author: Matthew T. Rondina, MD – Molecular Medicine Program, University of Utah, Salt Lake City, UT, USA; Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA; 4George E. Wahlen Department of Veterans Affairs Medical Center, Geriatric Research, Education, and Clinical Center; Department of Pathology, University of Utah School of Medicine, Salt Lake City, UT, USA
    Co-Author: Qian-fei Wang – Beijing Institute of Genomics, Chinese Academy of Sciences (CAS)
    Co-Author: Yueying Li, MD – Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0725 - Novel Resident Sites, Organ and Stage-Associated Diversity of Mammalian Megakaryocytes
    Room: Exhibition Hall
    Presenting Author: Meijuan Xia, PhD – Institute of Hematology&Blood Disease Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Cuicui Liu – Institute of Hematology, Blood Disease Hospital,Chinese Academy of Medical Science (CAMS)
    Co-Author: Yezi Ma – Institute of Hematology, Blood Disease Hospital,Chinese Academy of Medical Science (CAMS)
    Co-Author: Jingjing Zhao – Institute of Hematology, Blood Disease Hospital,Chinese Academy of Medical Science (CAMS)
    Co-Author: Hongtao Wang – State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Jiaxi Zhou, Ph.D – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0726 - Genetic engineering of megakaryocytes from blood progenitor cells using mRNA lipid nanoparticles
    Room: Exhibition Hall
    Presenting Author: Jerry Leung, PhD – The University of British Columbia
    Co-Author: Asel Primbetova – The University of British Columbia
    Co-Author: Colton Strong – The University of British Columbia
    Co-Author: Andrew Hagner – The University of British Columbia
    Co-Author: Dana Devine – The University of British Columbia
    Co-Author: Pieter R. Cullis – The University of British Columbia
    Co-Author: Peter W. Zandstra – The University of British Columbia
    Co-Author: Christian J. Kastrup – Versiti Blood Research Institute
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0727 - The role of PCSK9 in megakaryocyte reconstitution following hematopoietic stem cell transplantation
    Room: Exhibition Hall
    Presenting Author: Qi Wang, PhD – Department of Clinical Laboratory, Children’s Hospital of Soochow University
    Co-Author: Zheng Chen – Samsung company
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0728 - Role of the mechanotransductor PIEZO1 in megakaryocyte differentiation
    Room: Exhibition Hall
    Co-Author: Julien Demagny – HEMATIM UE4666, Univ. Picardie Jules Verne
    Co-Author: Sonia Poirault-Chassac – Université Paris Cité, Inserm UMR-S 1140
    Co-Author: Damtz Nehemie Ilsaint – HEMATIM UE4666, Univ. Picardie Jules Verne
    Co-Author: Aurore Marchelli – Université Paris Cité, Inserm UMR-S 1140
    Co-Author: Hakim Ouled-Haddou – HEMATIM UE4666, Univ. Picardie Jules Verne
    Co-Author: Maïlys Le Guyader – Biological Hematology Department, CHU Amiens-Picardie
    Co-Author: Pascale Gaussem – Université Paris Cité, Inserm UMR-S1140, Hôpital Européen Georges Pompidou
    Co-Author: Loïc Garçon – HEMATIM UE4666, Univ. Picardie Jules Verne
    Presenting Author: Christilla Bachelot-Loza, PhD – Université Paris Cité, Inserm UMR-S 1140
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0729 - Lung megakaryocyte compartment expands in response to LPS-induced acute lung injury
    Room: Exhibition Hall
    Presenting Author: Gabriel Leung – University of Utah
    Co-Author: Aaron Petrey – University of Utah
    Co-Author: Elizabeth Middleton – University of Utah
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0730 - Alterations in apoptosis and autophagy/ER-phagy signaling pathways contribute to the pathogenesis of immune thrombocytopenia
    Room: Exhibition Hall
    Presenting Author: Christina Bitsina, Msc – University Children’s Hospital Zürich, Division of Hematology, University of Zürich, Zürich, Switzerland
    Co-Author: Tea Stein – University Children’s Hospital Zürich, Division of Hematology, University of Zürich, Zürich, Switzerland
    Co-Author: Stacey Shllaku – University Children’s Hospital Zürich, Division of Hematology, University of Zürich, Zürich, Switzerland
    Co-Author: Nadine Gölz – University Children’s Hospital Zürich, Division of Hematology, University of Zürich, Zürich, Switzerland
    Co-Author: Markus Schmugge – University Children’s Hospital Zürich, Division of Hematology, University of Zürich, Zürich, Switzerland
    Co-Author: Francesca D. Franzoso – University Children’s Hospital Zürich, Division of Hematology, University of Zürich, Zürich, Switzerland
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0731 - Biology and pharmacokinetic study of natural and engineered megakaryoblastic exosomes
    Room: Exhibition Hall
    Presenting Author: Tuan Huu Nguyen, MD – Australian Centre for Blood Diseases (ACBD), Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University
    Co-Author: Rong Xu – Australian Centre for Blood Diseases (ACBD), Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University
    Co-Author: Bamlaku Walie – Australian Centre for Blood Diseases (ACBD), Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University
    Co-Author: Amir Roointan – Australian Centre for Blood Diseases (ACBD), Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University
    Co-Author: Siqi Li – Australian Centre for Blood Diseases (ACBD), Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University
    Co-Author: Christoph Hagemeyer – Australian Centre for Blood Diseases (ACBD), Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0732 - Platelet mitochondrial transfer alters neutrophil phenotype and function
    Room: Exhibition Hall
    Presenting Author: Harriet E. Allan, PhD – Queen Mary University of London
    Co-Author: Nicola Dark – Queen Mary University of London
    Co-Author: Plinio Ferreira – Imperial College London
    Co-Author: Marilena Crescente – Manchester Metropolitan University
    Co-Author: Timothy D. Warner – Queen Mary University of London
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0734 - Expression of miRNAs of platelet microvesicles in various oncopathologies
    Room: Exhibition Hall
    Presenting Author: Iryna Dremuk, PhD – Institute biophysics and cell engineering of NAS of Belarus
    Co-Author: Ekaterina Pashinskaya – Vitebsk State Medical University
    Co-Author: Yauheni Shliakhtunou – Vitebsk State Medical University
    Co-Author: Anastasia N. Sveshnikova – Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow, Russia
    Co-Author: Ekaterina V. Shamova, PhD – Institute of biophysics and cell engineering NAS of Belarus, Minsk, Belarus
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0735 - Contribution of platelet granule cargo uptake and secretion to the initiation and progression of aortic aneurysms
    Room: Exhibition Hall
    Presenting Author: Daniëlle M. Coenen, MD, PhD – Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, USA
    Co-Author: Sidney W. Whiteheart – University of Kentucky
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0736 - Platelets show functional specialization over their lifespan gaining proinflammatory function as they age in vitro and in circulation
    Room: Exhibition Hall
    Presenting Author: Leo Nicolai, MD – LMU Munich
    Co-Author: Afra Anjum – LMU Munich
    Co-Author: Magdalena Mader – LMU Munich
    Co-Author: Abhinaya Muraly – LMU Munich
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0737 - Platelet Protein Phosphatase 1c alpha Reduces Tumor Anoikis and Promotes Metastasis.
    Room: Exhibition Hall
    Co-Author: Deepika Subramanyam – Baylor College of Medicine/CTRID
    Co-Author: Robiya Joseph – MD Anderson Cancer Center
    Co-Author: Subhashree Pradhan – Baylor College of Medicine
    Co-Author: Vahid Afshar-Kharghan – MD Anderson Cancer Center
    Co-Author: Anil Sood – MD Anderson Cancer Center
    Presenting Author: K. Vinod Vijayan – Baylor College of Medicine/CTRID
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0738 - Elevated platelet reactivity is associated with blunted neurovascular haemodynamics in healthy middle age and older adults
    Room: Exhibition Hall
    Presenting Author: Joanne L. Dunster, PhD – Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University Of Reading
    Co-Author: Gabriella MK Rossetti – Centre for Integrative Neuroscience and Neurodynamics, School of Psychology and Clinical Language Sciences, University of Reading
    Co-Author: Aamir Sohail – Centre for Human Brain Health, School of Psychology, University of Birmingham
    Co-Author: Elysia Jewett – School of Biological Sciences, University of Reading
    Co-Author: Julie Lovegrove – Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading
    Co-Author: Jonathan M. Gibbins, PhD – Institute for Cardiovascular and Metabolic Research, School of Biological sciences, University of Reading, Reading, UK
    Co-Author: Anastasia Christakou – Centre for Integrative Neuroscience and Neurodynamics, School of Psychology and Clinical Language Sciences, University of Reading
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0739 - Optimization of in vitro and in vivo wound healing effect of platelet-rich plasma
    Room: Exhibition Hall
    Presenting Author: SANGGU KIM – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Co-Author: PREETI KUMARI CHAUDHARY, PhD – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Co-Author: SACHIN UPADHAYAYA – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Co-Author: Soochong Kim – Chungbuk National University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0740 - Selective inhibition of peptidylarginine deiminase 4 does not disrupt human platelet activation or aggregation ex vivo.
    Room: Exhibition Hall
    Presenting Author: Katrien Bomhals, MA – Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences - KU Leuven (Belgium)
    Co-Author: Sirima Kraisin – Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences - KU Leuven (Belgium)
    Co-Author: Marilena Crescente – Manchester Metropolitan University
    Co-Author: Kimberly Martinod – Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences - KU Leuven (Belgium)
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0741 - Platelet Count Recovery as a Pragmatic Diagnostic Tool for Predicting Mortality after Cardiac Surgery
    Room: Exhibition Hall
    Presenting Author: Nathan Clendenen – University of Colorado
    Co-Author: Elijah Christensen – University of Colorado
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0742 - LYOPHILIZED PLATELET WAFERS (LPCW) COLLAGEN AND CARBOXY METHYLCELLULOSE BASED PLATELET CONCENTRATE PREPARATION – IN VIVO & IN VITRO -PRELIMINARY STUDIES
    Room: Exhibition Hall
    Presenting Author: BARANIDHARAN G.R, MVSc PhD – TAMIL NADU VETERINARY AND ANIMAL SCIENCES UNIVERSITY
    Co-Author: MANGALA GOWRI A – TAMIL NADU VETERINARY AND ANIMAL SCIENCES UNIVERSITY
    Co-Author: NANDHINI S – TAMIL NADU VETERINARY AND ANIMAL SCIENCES UNIVERSITY
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0743 - Different occurrence of platelet-monocyte aggregates (PMA) in patients with different metabolic diseases and effect of direct anticoagulants
    Room: Exhibition Hall
    Presenting Author: Alejandro Carazo, PharmD PhD – Charles University, Faculty Of Pharmacy
    Co-Author: Lukáš Konečný – Charles University, Faculty Of Pharmacy
    Co-Author: Jaka Fadraersada – Charles University, Faculty Of Pharmacy
    Co-Author: Raúl Alva-Gallegos – Charles University, Faculty Of Pharmacy
    Co-Author: Pavel Skořepa – University Hospital Hradec Králové
    Co-Author: Kateřina Matoušová – University Hospital Hradec Králové
    Co-Author: Lenka Krčmová – Charles University, Faculty Of Pharmacy
    Co-Author: Markéta Paclíková – University Hospital Hradec Králové
    Co-Author: Milan Blaha – University Hospital Hradec Králové
    Co-Author: Vladimir Blaha – University Hospital Hradec Králové
    Co-Author: Přemysl Mladěnka – Charles University, Faculty Of Pharmacy
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0744 - Platelet-leucocyte aggregates are predictor of postoperative infection in patients with rheumatic heart disease
    Room: Exhibition Hall
    Presenting Author: Chaonan Liu, MD – West China Hospital, Sichuan University
    Co-Author: Jinghan Zhang – .Department of Anesthesiology,West China Hospital,Sichuan University,Chengdu, China
    Co-Author: Chuanmin Tao – Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China
    Co-Author: Jing Zhou – West China Hospital, Sichuan University
    Co-Author: Daming Gou – Department of Anesthesiology,Guizhou Maotai Hospital
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0745 - Effect of platelets on trained immunity in monocytes: a proof of concept study
    Room: Exhibition Hall
    Presenting Author: Dorien Salet – Amsterdam University Medical Center
    Co-Author: Bibian M.E. Tullemans – Radboud university medical center
    Co-Author: Laszlo Groh – Radboudumc
    Co-Author: Lucas L. van den Hoogen – Radboud university medical center
    Co-Author: Saskia Middeldorp, MD, PhD – Radboud university medical center
    Co-Author: Leo A.B. Joosten – Radboud university medical center
    Co-Author: Jenneke Leentjens – Department of Internal Medicine, Radboud Institute for Health Sciences, Radboud University Medical Centre
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0746 - Hexokinase2 regulates glycoprotein VI mediated glycolysis and platelet activation
    Room: Exhibition Hall
    Presenting Author: Lih T. Cheah, PhD – University of Leeds
    Co-Author: Jawad Khalil – University of Leeds
    Co-Author: Reem Alotaibi – University of Leeds
    Co-Author: Khalid M. Naseem – University of Leeds
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0747 - Targeting Na+/K+ ATPase alpha 1 subunit is a novel anti-platelet and anti-thrombotic therapy
    Room: Exhibition Hall
    Co-Author: Oliver LI – Joan C. Edwards School of Medicine at Marshall University
    Co-Author: Hong Yue – Joan C. Edwards School of Medicine at Marshall University
    Co-Author: Ellen Thompson – Joan C. Edwards School of Medicine at Marshall University
    Co-Author: Olga Fedorova – National Institute on Aging
    Co-Author: Sandrine Pierre – Joan C. Edwards School of Medicine at Marshall University
    Presenting Author: Wei Li, MD, PhD – Joan C. Edwards School of Medicine at Marshall University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0748 - Identification of key regulators of procoagulant COAT platelet generation by quantitative temporal phosphoproteomic analysis
    Room: Exhibition Hall
    Co-Author: Lucas Veuthey – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Presenting Author: Alessandro Aliotta, PhD – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Co-Author: Debora Bertaggia Calderara – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Co-Author: Lucas Gautier – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Co-Author: Cindy Pereira Portela – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Co-Author: Lorenzo Alberio – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0749 - Human Platelet Glycoprotein IIb is Glycosylated at the Polymorphic Serine Residue that Defines Human Platelet Antigen 3b
    Room: Exhibition Hall
    Co-Author: Akua A. Appah-Sampong – Brigham and Women's Hospital, Harvard Medical School
    Co-Author: Sarah C. Lowery – Yale University
    Co-Author: Isabella Tran – Yale University
    Co-Author: Keira Mahoney – Yale University
    Co-Author: James Lee – Brigham and Women's Hospital, Harvard Medical School
    Co-Author: Stacy A. Malaker – Yale University
    Presenting Author: Marie A. Hollenhorst, MD PhD – Brigham and Women's Hospital, Harvard Medical School
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0750 - The Exocyst component Sec10/EXOC5 plays a role in platelet granule secretion and trafficking
    Room: Exhibition Hall
    Presenting Author: Smita Joshi, PhD – Morehead State University
    Co-Author: Sidney W. Whiteheart – University of Kentucky
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0752 - Competitive inhibition of TLT-1/fibrinogen molecular interaction disrupts platelet function in ex vivo platelet assays.
    Room: Exhibition Hall
    Presenting Author: Siobhan L. Branfield – Oakland University
    Co-Author: Xariana Vales – Stanford University
    Co-Author: Susan Lagrand – Oakland University
    Co-Author: Colin Wu – Oakland University
    Co-Author: Barbara Manfredi – Oakland University
    Co-Author: Pearl Akamine – University of Puerto Rico
    Co-Author: Yadira Marie Cantres – Oakland University
    Co-Author: Jose González – University of Puerto Rico
    Co-Author: Abel Baerga – University of Puerto Rico
    Co-Author: Loyda Melendez Aponte – University of Puerto Rico
    Co-Author: Valance Washington – Oakland University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0753 - Tryptanthrin inhibits platelet functions and thrombosis
    Room: Exhibition Hall
    Presenting Author: Hanchen Gao – The First Affiliated Hospital, Zhejiang University School of Medicine
    Co-Author: Xiangjie Lin – The First Affiliated Hospital, Zhejiang University School of Medicine
    Co-Author: Jie Jin – The First Affiliated Hospital, Zhejiang University School of Medicine
    Co-Author: Jiansong Huang – The First Affiliated Hospital, Zhejiang University School of Medicine
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0754 - MICAL1, a new actor in platelets, governing shear-dependent adhesive and thrombotic functions of platelets via actin regulation within the GPIb complex.
    Room: Exhibition Hall
    Presenting Author: Jean Solarz – INSERM U1176, Université Paris Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Christelle Soukaseum – INSERM U1176, Université Paris Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Christelle Repérant – INSERM U1176, Université Paris Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Stéphane Frémont – Institut Pasteur, Université Paris Cité, CNRS UMR3691, Paris, France
    Co-Author: Thibaud Séfiane – INSERM U1176, Université Paris Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Valérie Proulle – INSERM U1138, Centre de Recherche des Cordeliers, CNRS, Sorbonne Université, Université Paris Cité, Paris, France ; Service d'Hématologie Biologique et Unité Fonctionnelle d'Hémostase, Hôpital Cochin, AP-HP Centre, Université Paris Cité, Paris, France
    Co-Author: Elisa Rossi – INSERM U1140, Université Paris Cité, Paris, France
    Co-Author: Jean-Claude Bordet – UR4609 Hémostase & Thrombose, Université Claude Bernard Lyon, Lyon, France
    Co-Author: Cécile V. Denis – INSERM U1176, Université Paris Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Dominique Baruch – INSERM U1140, Université Paris Cité, Paris, France
    Co-Author: Pierre H. Mangin, PhD – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, Strasbourg, France
    Co-Author: Yacine Boulaftali – INSERM U1148, Université Paris Cité, Paris, France
    Co-Author: R. Jeroen Pasterkamp – Department of Translational Neuroscience, University Medical Center Utrecht, Brain Center, Utrecht University, Utrecht, The Netherlands
    Co-Author: Hana Raslova – INSERM U1287, Gustave Roussy, Université Paris Saclay, Villejuif, France
    Co-Author: Arnaud Echard – Institut Pasteur, Université Paris Cité, CNRS UMR3691, Paris, France
    Co-Author: Frédéric Adam – INSERM U1176, Université Paris Saclay, Le Kremlin-Bicêtre, France
    Co-Author: Alexandre KAUSKOT, PhD – INSERM U1176, Hôpital Bicêtre
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0755 - GPVI and CD36 expression predict a prothrombotic platelet phenotype
    Room: Exhibition Hall
    Co-Author: Alexander P. Bye – University of Reading
    Co-Author: neline kriek – University of Reading
    Co-Author: Carly Kempster – University Of Reading
    Co-Author: Joanne L. Dunster, PhD – Institute for Cardiovascular and Metabolic Research, School of Biological Sciences, University Of Reading
    Co-Author: Joanne Mitchell – University Of Birmingham
    Co-Author: Tanya Sage – University Of Reading
    Co-Author: suzannah Rawlings – University Of Reading
    Co-Author: abigail Whyte – Royal Berkshire Hospital
    Co-Author: Leanne Dymott – Royal Berkshire Hospital
    Co-Author: sharon Mark – Royal Berkshire Hospital
    Co-Author: Mark Brunton – Royal Berkshire Hospital
    Co-Author: Joana Batista – University of Cambridge
    Co-Author: Harriet McKinney – University of Cambridge
    Co-Author: Patrick Thomas – University of Cambridge
    Co-Author: Kate Downes – NHS East Genomic Laboratory Hub
    Co-Author: Neil Ruperelia – Imperial College Healthcare NHS Trust
    Co-Author: Charlie McKenna – Royal Berkshire Hospital
    Co-Author: Chris Jones – University Of Reading
    Co-Author: Amanda J. Unsworth, DPhil – Manchester Metropolitan University
    Presenting Author: Jonathan M. Gibbins, PhD – Institute for Cardiovascular and Metabolic Research, School of Biological sciences, University of Reading, Reading, UK
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0756 - A Novel Potent Inhibitor of Protein Disulfide Isomerase Suppresses Platelet Aggregation and Thrombus Formation
    Room: Exhibition Hall
    Presenting Author: Lili Zhang – Huazhong University of Science and Technology
    Co-Author: Keyu Lv, phD – Huazhong University of Science and Technology
    Co-Author: Hao Wang – Huazhong University of Science and Technology
    Co-Author: Guijuan Zheng – Huazhong University of Science and Technology
    Co-Author: Xulin Xu – Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology
    Co-Author: Mingdong Huang – College of Chemistry, Fuzhou University
    Co-Author: Guangmin Yao – Huazhong University of Science and Technology
    Co-Author: Chao Fang, PhD – Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0757 - Divergent functions of canonical integrin activation complex proteins during platelet migration and inflammatory hemostasis
    Room: Exhibition Hall
    Presenting Author: Matthew VanderPloeg – UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.
    Co-Author: Mitchell Butler – UNC Lineberger Comprehensive Cancer Center, UNC-Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States
    Co-Author: Ansh Gulati – University of North Carolina at Chapel Hill, Chapel Hill, NC.
    Co-Author: Elizabeth Davis – Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.
    Co-Author: Harrison Truscott – University of North Carolina at Chapel Hill, Chapel Hill, NC.
    Co-Author: Robert Lee – UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.
    Co-Author: James Bear – UNC Lineberger Comprehensive Cancer Center, UNC-Chapel Hill School of Medicine, Chapel Hill, North Carolina 27599, United States.
    Co-Author: Wolfgang Bergmeier – UNC Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0758 - An αIIbβ3 Ligand-Mimetic mAb Shows Platelet Activation (via Engaging FcγIIA Receptor) and Inhibition (via blocking αIIbβ3 Ligand Binding) and Serves as a Model of Disorders Involving FcγRIIA
    Room: Exhibition Hall
    Presenting Author: Lorena Buitrago – Rockefeller University
    Co-Author: Jialing Wang – The Rockefeller University
    Co-Author: Lu Wang – The Rockefeller University
    Co-Author: Jihong Li – The Rockefeller University
    Co-Author: Thomas Walz – The Rockefeller University
    Co-Author: Barry Coller – Rockefeller University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0759 - MicroRNA-223-3p decreases platelet procoagulant activity through the regulation of TMEM16F
    Room: Exhibition Hall
    Co-Author: Julia Charlon – University of Geneva
    Co-Author: Sylvie Dunoyer-Geindre – University of Geneva
    Co-Author: Séverine Nolli – University of Geneva
    Co-Author: Paulina Ciepla – University of Geneva
    Co-Author: Jean-Luc Reny – Division of General Internal Medicine, Geneva University Hospitals
    Presenting Author: Pierre Fontana – Division of Angiology and Hemostasis, Geneva University Hospitals
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0760 - Wilson's disease - platelet function and platelet-related novel biomarkers for hepatic manifestation
    Room: Exhibition Hall
    Co-Author: Marta Wolska – Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Center for Preclinical Research and Technology CEPT, Warsaw, Poland
    Co-Author: Zofia Wicik – Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Center for Preclinical Research and Technology CEPT, Warsaw, Poland
    Co-Author: Sara Ahmadova – Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Center for Preclinical Research and Technology CEPT, Warsaw, Poland
    Co-Author: Anna Nowak – Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Center for Preclinical Research and Technology CEPT, Warsaw, Poland
    Co-Author: Aleksandra Gasecka – Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
    Co-Author: Marek Postula – Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Center for Preclinical Research and Technology CEPT, Warsaw, Poland
    Co-Author: Anna Czlonkowska – 2nd Department of Neurology Institute of Psychiatry and Neurology Warsaw Poland
    Presenting Author: Ceren Eyileten Postula, N/A – Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Center for Preclinical Research and Technology CEPT, Warsaw, Poland
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0761 - Differential interactions of energy metabolism inhibitors – CORM-A1 and 3PO – with cangrelor in terms of platelet antiaggregatory effect
    Room: Exhibition Hall
    Co-Author: Anna Kurpinska – Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Co-Author: Elena Lytvynenko – Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Co-Author: Agnieszka Kij – Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Co-Author: Kamil Przyborowski – Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Co-Author: Stefan Chlopicki – Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Presenting Author: Patrycja Kaczara, PhD – Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0762 - Storage and Characterization of mRNA-Lipid Nanoparticle Engineered Platelets
    Room: Exhibition Hall
    Presenting Author: Emma Kang – University of British Columbia
    Co-Author: Colton Strong – The University of British Columbia
    Co-Author: Jerry Leung, PhD – The University of British Columbia
    Co-Author: Katherine Badior – Versiti Blood Research Institute
    Co-Author: Madelaine Robertson – The University of British Columbia
    Co-Author: Nicolas Pereyra – The University of British Columbia
    Co-Author: Elyn Rowe – The University of British Columbia
    Co-Author: Amanda Wietrzny – Versiti Blood Research Institute
    Co-Author: Brenda Ma – The University of British Columbia
    Co-Author: Zechariah Noronha – University of British Columbia
    Co-Author: Deaglan Arnold – Nanovation Therapeutics
    Co-Author: Marco A. Ciufolini – The University of British Columbia
    Co-Author: Dana Devine – The University of British Columbia
    Co-Author: Eric Jan – The University of British Columbia
    Co-Author: Pieter R. Cullis – The University of British Columbia
    Co-Author: Christian J. Kastrup – Versiti Blood Research Institute
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0763 - Rgl1, an activator of the Ral signalling pathway, is a novel regulator of platelet activation and thrombosis
    Room: Exhibition Hall
    Co-Author: Maria Lopes-Pires – Imperial College London
    Co-Author: Mascha Vinokurova – Imperial College London
    Co-Author: Jane Mitchell – Imperial College London
    Presenting Author: Nicholas Kirkby – Imperial College London
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0764 - Farnesyltransferase inhibitor tipifarnib regulates platelet function through thromboxane A2 generation
    Room: Exhibition Hall
    Presenting Author: PREETI KUMARI CHAUDHARY, PhD – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Co-Author: SANGGU KIM – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Co-Author: SACHIN UPADHAYAYA – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Co-Author: SOOCHONG KIM – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0765 - Glycoprotein VI is an interesting target to prevent early stent thrombosis in different arterial territories
    Room: Exhibition Hall
    Presenting Author: Axelle Y. KERN, MSc – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Dihia Chebbah – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, F-67065 Strasbourg, France
    Co-Author: Camille Robert – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, Strasbourg, France
    Co-Author: Yevgeniy Kreinin – Department of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel
    Co-Author: Anne Lejay – Vascular Surgery and Renal Transplantation Department, Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Salomé Kuntz – Vascular Surgery and Renal Transplantation Department, Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Martine Jandrot-Perrus, MD., PhD. – Laboratory for Vascular Translational Science, UMR_S1148 INSERM, University Paris Cité, Hôpital Bichat, Paris, France
    Co-Author: Nabil Chakfé – Vascular Surgery and Renal Transplantation Department, Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Raoul Pop – Interventional Neuroradiology Department, Strasbourg University Hospitals, Strasbourg, France
    Co-Author: Netanel Korin – Department of Biomedical Engineering, Technion - Israel Institute of Technology, Haifa, Israel
    Co-Author: Pierre H. Mangin, PhD – University of Strasbourg, INSERM, EFS Grand-Est, BPPS UMR-S1255, FMTS, Strasbourg, France
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0766 - Molecular, Morphological, and Functional Transition of Platelets during Mammalian Development
    Room: Exhibition Hall
    Presenting Author: Baiming Huang – State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Cuicui Liu – Institute of Hematology, Blood Disease Hospital,Chinese Academy of Medical Science (CAMS)
    Co-Author: Le Li – Institute of Hematology, Blood Disease Hospital,Chinese Academy of Medical Science (CAMS)
    Co-Author: Yue Feng – State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Pei Su – State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Hongtao Wang – State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Hong Wang – State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
    Co-Author: Jiaxi Zhou, Ph.D – Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0768 - Mitochondrial calcium uniporter as a key regulator in the generation of procoagulant COAT platelets
    Room: Exhibition Hall
    Presenting Author: Durre Shehwar – Quaid-i-Azam University
    Co-Author: Alessandro Aliotta, PhD – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Co-Author: Saima Barki – Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan
    Co-Author: Debora Bertaggia Calderara – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Co-Author: Lucas Veuthey – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Co-Author: Cindy Pereira Portela – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Co-Author: Muhammad Rizwan Alam – Department of Biochemistry, Quaid-i-Azam University, Islamabad, Pakistan
    Co-Author: Lorenzo Alberio – Division of Hematology and Central Hematology Laboratory, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0769 - The role of functional ectonucleotidases in human platelet activation signaling
    Room: Exhibition Hall
    Presenting Author: Susheel N. Chaurasia, MSc, PhD – Center for Advanced Research on Platelet Signaling and Thrombosis Biology, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India
    Co-Author: Geeta Kushwaha – Center for Advanced Research on Platelet Signaling and Thrombosis Biology, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University; Varanasi-221005, Uttar Pradesh, India
    Co-Author: Abhishek Pandey – Department of Medicine, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India
    Co-Author: Debabrata Dash – Center for Advanced Research on Platelet Signaling and Thrombosis Biology, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University; Varanasi-221005, Uttar Pradesh, India
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0770 - Cold storage iPS-platelets display comparable hemostatic capability to cold human platelets
    Room: Exhibition Hall
    Presenting Author: WEIYIN QIU – Kyoto University
    Co-Author: Sou Nakamura – Kyoto University
    Co-Author: Haruki Okamoto – Kyoto University
    Co-Author: Koji Eto – Kyoto University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0771 - Testosterone Replacement Therapy Does Not Alter Stored Platelet Hemostatic Capacity
    Room: Exhibition Hall
    Co-Author: Alisha Chitrakar – Vitalant Research Institute
    Co-Author: Scott-Wesley M. Bean – Vitalant Research Institute
    Presenting Author: Kimberly A. Thomas – Vitalant Research Institute
    Co-Author: Tamir Kanias – Vitalant Research Institute
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0772 - Secondary activation of platelets is responsible for increased desialylation of platelets of ITP patients
    Room: Exhibition Hall
    Presenting Author: Olga An, MD – University Medical Center Mainz, Center for Thrombosis and Hemostasis
    Co-Author: Alexey Martyanov – Dmitry Rogachev National Medical Research Centеr of Pediatric Hematology, Oncology and Immunology
    Co-Author: Varvara Vasilevskaya – M.V.Lomonosov Moscow State University, Faculty of Physics, Moscow, Russia
    Co-Author: Anastasia Tarakanova – Center for Theoretical Problems of Physico-Chemical Pharmacology RAS, Moscow, Russia
    Co-Author: Anastasia Ignatova – Dmitry Rogachev National Medical Research Centеr of Pediatric Hematology, Oncology and Immunology
    Co-Author: Mikhail Panteleev – Center for Theoretical Problems of Physico-Сhemical Pharmacology
    Co-Author: Carsten Deppermann, PhD – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz
    Co-Author: Anastasia N. Sveshnikova – Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow, Russia
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0773 - Single-platelet immunophenotyping of temporally-defined sub-populations in mice
    Room: Exhibition Hall
    Co-Author: Ami Vadgama – Queen Mary University of London
    Co-Author: James Boot – Queen Mary University of London
    Co-Author: Harriet E. Allan, PhD – Queen Mary University of London
    Co-Author: Timothy D. Warner – Queen Mary University of London
    Presenting Author: Paul Armstrong – Queen Mary University of London
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0774 - Development and Characterization of Conditional Nbeal2 KO Mouse Strains for studies of Thrombo-Inflammation
    Room: Exhibition Hall
    Presenting Author: Katrina Ashworth – Washington University Saint Louis
    Co-Author: Thomas Girard – Washington University Saint Louis
    Co-Author: Renu Subramanian – Washington University SAint Louis
    Co-Author: NIna Lasky – Washington University Saint Louis
    Co-Author: Jorge Di Paola, MD – Washington University School of Medicine
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0775 - Platelet TNIK promotes hemostasis while prevents hyperlipidemia-associated thrombosis
    Room: Exhibition Hall
    Presenting Author: Fan Bu – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
    Co-Author: Li Li – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
    Co-Author: Jingke Li – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
    Co-Author: Xiaoyan Chen – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
    Co-Author: Xin Deng – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
    Co-Author: Yilin Sheng – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
    Co-Author: Hu Hu, PhD – Department of Pathology and Pathophysiology and Bone Marrow Transplantation Center of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China and Institute of Hematology, Zhejiang University & Zhejiang Engineering Laboratory for Stem Cell and Immunotherapy, Hangzhou, China.
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0777 - Platele's function and sialylation in aged individuals
    Room: Exhibition Hall
    Presenting Author: Elena Monzón Manzano – Department of Haematology, Hospital Universitario La Paz, Madrid, Spain. IdiPAZ, Madrid, Spain
    Co-Author: María Teresa Alvarez-Román, MD, PhD – Department of Hematology, University Hospital La Paz, Autonoma University of Madrid, Madrid, Spain
    Co-Author: Carmen Herrero Carrasco – Hospital Severo Ochoa
    Co-Author: Paula Acuña Butta – Department of Haematology, Hospital Universitario La Paz-IdiPaz
    Co-Author: Elena G.Arias Salgado – Grupo de Coagulopatías y Trastornos de la Hemostasia, IdiPaz, Madrid, Spain
    Co-Author: Raquel Ramirez Martín – Department of Geriatrics, Hospital Universitario La Paz- IdiPaz
    Co-Author: Mónica Martín Salces – Department of Haematology, Hospital Universitario La Paz-IdiPaz
    Co-Author: Isabel Rivas Pollmar – Department of Haematology, Hospital Universitario La Paz-IdiPaz
    Co-Author: Víctor Jiménez-Yuste – Hospital Universitario La Paz-IdiPaz
    Co-Author: Pedro Sanchez Godoy – Hospital Severo Ochoa
    Co-Author: Nora Butta – Grupo de Coagulopatías y Trastornos de la Hemostasia, IdiPaz, Madrid, Spain
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0778 - Effects of Intravenous Iron Infusion on Platelet Function in Orthopedic Trauma Patients
    Room: Exhibition Hall
    Presenting Author: Chih-Jen Yang, MD – Oregon Health & Science University
    Co-Author: Victoria Duke – Oregon Health & Science University
    Co-Author: Michaela Geffert – Oregon Health & Science University
    Co-Author: Danielle Peterson – Oregon Health & Science University
    Co-Author: Natasha McKibben – Oregon Health & Science University
    Co-Author: Catherine Hutchison – Oregon Health & Science University
    Co-Author: Nick Willett – University of Oregon
    Co-Author: Joseph Shatzel – Oregon Health & Science University
    Co-Author: Zachary Working – Oregon Health & Science University
    Co-Author: Joe Aslan, PhD – Oregon Health & Science University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0779 - Anticoagulant effects of a new inhibitor of PDI isomerases
    Room: Exhibition Hall
    Presenting Author: Agnieszka Pelesz, MSc Eng – 1Jagiellonian University, Doctoral School of Exact and Natural Sciences, Krakow, Poland 2 Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Co-Author: Kamil Przyborowski – Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Co-Author: Stefan Chlopicki – Jagiellonian University in Krakow, Jagiellonian Centre for Experimental Therapeutics
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0780 - Elucidation of the mechanism of intraoperative and postoperative bleeding tendency associated with prolonged extracorporeal circulation time.
    Room: Exhibition Hall
    Presenting Author: Hohomi Arao – Kumamoto Health Science University
    Co-Author: Tatsuya Furugaki – University of Tsukuba Hospital
    Co-Author: Tatsuya Kawaguchi – Kumamoto Health Science University
    Co-Author: Yukinori Kozuma – Kumamoto Health Science University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0781 - Liposome-assisted uptake of procoagulant proteins by platelets
    Room: Exhibition Hall
    Presenting Author: Herm Jan Brinkman – Sanquin Research
    Co-Author: Marleen Zuurveld – Sanquin Research
    Co-Author: Sanne Dekker – Sanquin Research
    Co-Author: Dave Ter Horst – Sanquin Research
    Co-Author: Erik Mul – Sanquin Research
    Co-Author: Mark Hoogenboezem – Sanquin Research
    Co-Author: Joost Meijers – Sanquin Research
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0782 - The role of Immature Platelet Fraction in determining the need for transfusion and predicting thrombopoietic recovery in patients undergoing cytotoxic chemotherapy
    Room: Exhibition Hall
    Co-Author: Maha El Amani – Ibn Sina University Hospital of Rabat / Mohammed V Military Traning Hospital - Faculty of medicine and Pharmacy of Rabat
    Co-Author: Naoufal Benlachgar – CHU Ibn Sina
    Co-Author: Soukaina Haidouri – CHU Ibn Sina
    Co-Author: Mamad Hassan – CHU Ibn Sina
    Co-Author: Azlarab Masrar – CHI Ibn Sina
    Presenting Author: Zoubida Tazi Mezalek – Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0783 - Characterization of P-selectin and TLT-1 interaction to regulate hemostatic function.
    Room: Exhibition Hall
    Presenting Author: Barbara Manfredi – Oakland University
    Co-Author: Andrea Acsiniuc – Oakland University
    Co-Author: Jessica Morales-Ortiz – Eli Lilly and Company
    Co-Author: Valance Washington – Oakland University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0784 - Сollagen fibres orientation strongly affects platelet adhesion at high shear
    Room: Exhibition Hall
    Presenting Author: Evgeniia A. Melnikova, MA – Center for Theoretical Problems of Physicochemical Pharmacology
    Co-Author: Mikhail Panteleev – Center for Theoretical Problems of Physico-Сhemical Pharmacology
    Co-Author: Dmitry Nechipurenko, PhD – M.V.Lomonosov Moscow State University, Faculty of Physics
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0786 - Mechanisms and Mediators of Stroke in patients with Fibromuscular Dysplasia
    Room: Exhibition Hall
    Presenting Author: Edelyn Huijun Park – Cleveland Clinic
    Co-Author: Natalia Fendrikova-Mahlay – Cleveland Clinic
    Co-Author: Anu Aggarwal – Cleveland Clinic
    Co-Author: Suman Guntupalli – Cleveland Clinic
    Co-Author: Matthew Godwin – Cleveland Clinic
    Co-Author: Alliefair Scalise – Cleveland Clinic
    Co-Author: Bhairavi Rajasekar – Cleveland Clinic
    Co-Author: Pulkit Chaudhury – Cleveland Clinic
    Co-Author: Emily Manning – Cleveland Clinic
    Co-Author: Esther Kim – Atrium Health
    Co-Author: Kimberly Peterson – Cleveland Clinic
    Co-Author: Mariya Ali – Cleveland Clinic
    Co-Author: Scott J. Cameron, PhD, MD – Cleveland Clinic
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0787 - Role of selected microRNAs in regulation of hemostasis in zebrafish larvae
    Room: Exhibition Hall
    Co-Author: Paulina Ciepla – University of Geneva
    Co-Author: Richard J. Fish – University of Geneva
    Co-Author: Séverine Nolli – University of Geneva
    Co-Author: Sylvie Dunoyer-Geindre – University of Geneva
    Co-Author: Julia Charlon – University of Geneva
    Co-Author: Jean-Luc Reny – Division of General Internal Medicine, Geneva University Hospitals
    Co-Author: Marguerite Neerman-Arbez – University of Geneva
    Presenting Author: Pierre Fontana – Division of Angiology and Hemostasis, Geneva University Hospitals
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0788 - Blood clot contraction depends both on clot shape and volume
    Room: Exhibition Hall
    Presenting Author: Rafael R. Khismatullin, MD PhD – Kazan Federal University, Institute of Fundamental Medicine and Biology
    Co-Author: Shakhnoza M. Saliakhutdinova – Kazan Federal University, Institute of Fundamental Medicine and Biology
    Co-Author: Alina I. Khabirova – Kazan Federal University, Institute of Fundamental Medicine and Biology
    Co-Author: Rustem I. Litvinov – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Co-Author: John W. Weisel – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0789 - Temporal dynamics of MLKL: pivotal roles in agonist-induced platelet prothrombotic responses and lytic cell death.”
    Room: Exhibition Hall
    Presenting Author: Vipin Singh – Center for Advanced Research on Platelet Signaling and Thrombosis Biology, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India
    Co-Author: Debabrata Dash – Center for Advanced Research on Platelet Signaling and Thrombosis Biology, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India
    Co-Author: Mohammad Ekhlak – Center for Advanced Research on Platelet Signaling and Thrombosis Biology, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India
    Co-Author: Susheel N. Chaurasia, MSc, PhD – Center for Advanced Research on Platelet Signaling and Thrombosis Biology, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India
    Co-Author: Paresh P. Kulkarni P. Kulkarni – Center for Advanced Research on Platelet Signaling and Thrombosis Biology, Department of Biochemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India
    Co-Author: Rameshwar Nath Chaurasia – Department of Neurology, Banaras Hindu University Institute of Medical Sciences: Varanasi, Uttar Pradesh, IN
    Co-Author: Saroj Kant Mohapatra – National Institute of Biomedical Genomics, Kalyani, India.
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0790 - Procoagulant platelets and thrombus architecture in mouse tail vein bleeding model
    Room: Exhibition Hall
    Presenting Author: Sergei I. Obydennyi, PhD – Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, Moscow, Russia
    Co-Author: Nikita Nikitin – Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, Moscow, Russia
    Co-Author: Ruzanna Ovsepyan – Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, Moscow, Russia
    Co-Author: Anastasiia Kuznetsova – Center for Theoretical Problems of Physico-Chemical Pharmacology, Russian Academy of Sciences, Moscow, Russia
    Co-Author: Mikhail Panteleev – Center for Theoretical Problems of Physico-Сhemical Pharmacology
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0791 - An approach for whole blood platelet flow cytometry and standardization across instruments
    Room: Exhibition Hall
    Presenting Author: Jillian Teichman, B.Sc. – National Heart, Lung and Blood Institute
    Co-Author: Andrew D. Johnson, PhD – NHLBI
    Co-Author: Amber Lachapelle – NIH
    Co-Author: Melissa V. Chan – NIH
    Co-Author: Sara Yi – NHLBI
    Co-Author: Robin Pashek – NHLBI
    Co-Author: Bongani B Nkambule – University of Kwazulu-Natal
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0792 - The effect of aceclofenac and etoricoxib on platelet aggregation activity in bone trauma
    Room: Exhibition Hall
    Co-Author: Anastasia D. Aleksandrova – Ural State Medical University
    Presenting Author: Irina P. Antropova – Ural State Medical University
    Co-Author: Maria N. Dobrinskaya – Ural State Medical University
    Co-Author: Anna V. Sukhoguzova – Urals State Medical University
    Co-Author: Elena I. Panasenko – Institute of Natural Sciences and Mathematics of the Ural Federal University
    Co-Author: Sergey L. Khatsko – Institute of Natural Sciences and Mathematics of the Ural Federal University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0793 - Continuous flow cytometry analysis of calcium signaling and mitochondrial function in human platelets
    Room: Exhibition Hall
    Presenting Author: Artem A. Mishukov – Center for Theoretical Problems of Physico-Chemical Pharmacology RAS
    Co-Author: Anastasia Tarakanova – Center for Theoretical Problems of Physico-Chemical Pharmacology RAS, Moscow, Russia
    Co-Author: Anna Ogneva – Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology, and Immunology, Moscow, Russia
    Co-Author: Anna Boldova, PhD – Center for Theoretical Problems of Physicochemical Pharmacology
    Co-Author: Mikhail Panteleev – Center for Theoretical Problems of Physico-Сhemical Pharmacology
    Co-Author: Anna Shcherbina – Dmitry Rogachev National Medical Research Centеr of Pediatric Hematology, Oncology and Immunology
    Co-Author: Anastasia N. Sveshnikova – Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology, Moscow, Russia
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0794 - Effects of antiplatelet drugs on platelet procoagulant reactions
    Room: Exhibition Hall
    Presenting Author: Ivan Muravlev, PhD – Chazov National Medical Research Center of Cardiology, Russian Ministry of Health
    Co-Author: Anatoly Dobrovolsky – Chazov National Medical Research Center of Cardiology, Russian Ministry of Health
    Co-Author: Olga A. Antonova, PhD – Chazov National Medical Research Center of Cardiology, Russian Ministry of Health
    Co-Author: Svetlana Khaspekova – Chazov National Medical Research Center of Cardiology, Russian Ministry of Health
    Co-Author: Amina Alieva – Chazov National Medical Research Center of Cardiology, Russian Ministry of Health
    Co-Author: Dmitry Pevzner – Chazov National Medical Research Center of Cardiology, Russian Ministry of Health
    Co-Author: Alexey Mazurov – Chazov National Medical Research Center of Cardiology, Russian Ministry of Health
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0796 - Lupus Anticoagulant-positive Patients with Thrombosis History have Altered Glycoprotein IIbIIIa Levels
    Room: Exhibition Hall
    Presenting Author: Theresa Schramm, MSc – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna
    Co-Author: Felicia Hsu – Institute of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna
    Co-Author: Anahita Sedighi – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna
    Co-Author: Waltraud Schrottmaier – Institute of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna
    Co-Author: Cihan Ay, MD – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna
    Co-Author: Ingrid Pabinger – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna
    Co-Author: Maria Zellner – Institute of Vascular Biology and Thrombosis Research, Centre for Physiology and Pharmacology, Medical University of Vienna
    Co-Author: Johanna Gebhart – Department of Internal Medicine I, Clinical Division of Hematology and Haemostaseology, Medical University of Vienna
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0798 - Age-related changes in coagulation of healthy individuals evaluated by global tests
    Room: Exhibition Hall
    Presenting Author: Paula Acuña Butta – Department of Haematology, Hospital Universitario La Paz-IdiPaz
    Co-Author: Elena Monzón Manzano – Department of Haematology, Hospital Universitario La Paz, Madrid, Spain. IdiPAZ, Madrid, Spain
    Co-Author: Elena G.Arias Salgado – Grupo de Coagulopatías y Trastornos de la Hemostasia, IdiPaz, Madrid, Spain
    Co-Author: Carmen Herrero Carrasco – Hospital Severo Ochoa
    Co-Author: Raquel Ramirez Martín – Department of Geriatrics, Hospital Universitario La Paz- IdiPaz
    Co-Author: Mónica Martín Salces – Department of Haematology, Hospital Universitario La Paz-IdiPaz
    Co-Author: Isabel Rivas Pollmar – Department of Haematology, Hospital Universitario La Paz-IdiPaz
    Co-Author: Víctor Jiménez-Yuste – Hospital Universitario La Paz-IdiPaz
    Co-Author: Pedro Sanchez Godoy – Hospital Severo Ochoa
    Co-Author: María Teresa Alvarez-Román, MD, PhD – Department of Hematology, University Hospital La Paz, Autonoma University of Madrid, Madrid, Spain
    Co-Author: Nora Butta – Grupo de Coagulopatías y Trastornos de la Hemostasia, IdiPaz, Madrid, Spain
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0802 - Eight-year body mass index trajectories are associated with altered platelet reactivity traits in Framingham Heart Study participants
    Room: Exhibition Hall
    Co-Author: Bongani B Nkambule – University of Kwazulu-Natal
    Co-Author: Melissa V. Chan – NIH
    Co-Author: Amber Lachapelle – NIH
    Co-Author: Ming-Huei Chen – National Heart, Lung, and Blood Institute
    Presenting Author: Andrew D. Johnson, PhD – NHLBI
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0804 - The effect of clinically used antiplatelets drugs and flavonoid metabolite 4-methylcatechol in diabetes mellitus type I patients and generally healthy volunteers.
    Room: Exhibition Hall
    Presenting Author: Lukáš Konečný, MSc – The Department of Pharmacology and Toxicology, Faculty of Pharmacy in Hradec Králové, Charles University
    Co-Author: Alejandro Carazo, PharmD PhD – Charles University, Faculty Of Pharmacy
    Co-Author: Markéta Paclíková – University Hospital Hradec Králové
    Co-Author: Přemysl Mladěnka – Charles University, Faculty Of Pharmacy
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0805 - Platelet indices as a predictive marker in neonatal sepsis and respiratory distress in preterm prelabor rupture of membranes
    Room: Exhibition Hall
    Presenting Author: sanjay mishra – KIng George's medical university, Lucknow
    Co-Author: Jaiswar shyampyari – King Georges medical University, Lucknow
    Co-Author: saad sumaiya – King Georges medical University, Lucknow
    Co-Author: Mishra Neetu – SML diagnostics
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0807 - Essential role of glycoprotein Ibα in von Willebrand factor-independent platelet activation
    Room: Exhibition Hall
    Presenting Author: Rong Yan – The First Affiliated Hospital of Soochow University
    Co-Author: Yue Xia – The First Affiliated Hospital of Soochow University
    Co-Author: Kangxi Zhou – The First Affiliated Hospital of Soochow University
    Co-Author: Jun Liu – The First Affiliated Hospital of Soochow University
    Co-Author: Changgeng Ruan – The First Affiliated Hospital of Soochow University
    Co-Author: Kesheng Dai – The First Affiliated Hospital of Soochow University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0808 - The L33P polymorphism of integrin β3 PSI domain displays enhanced thiol isomerase activity and upregulates the coagulation cascade
    Room: Exhibition Hall
    Co-Author: Brock K. Hoard – University of Toronto
    Co-Author: Eric Cerenzia – University of Toronto
    Co-Author: Preeti Bhoria – St. Michaels Hospital
    Co-Author: Sladjana Slavkovic – St. Michael's Hospital
    Co-Author: Pingguo Chen – St Michael's Hospital
    Co-Author: Xi Lei – St. Michael's Hospital
    Co-Author: Guangheng Zhu – St. Michael's Hospital
    Co-Author: Andras Kapus – University of Toronto
    Co-Author: Kim Connelly – St. Michael's Hospital
    Presenting Author: Heyu Ni, MD, PhD – University of Toronto / Canadian Blood Services
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0810 - Oxidized-LDL Induces two Distinct Platelet Phenotypes: Aggregatory Platelets Through Gq-Dependent ASK1 Activation and Procoagulant Platelets Through CD36 Dependent SFK Activation
    Room: Exhibition Hall
    Presenting Author: Meghna U. Naik, MS – Thomas Jefferson University
    Co-Author: Kalyan Golla – Thomas Jefferson University
    Co-Author: Ulhas P. Naik – Thomas Jefferson University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0811 - Cryo-EM structure of a GPIb-IX quaternary complex and implications for platelets activation and Bernard-Soulier syndrome
    Room: Exhibition Hall
    Co-Author: Aiwu Zhou – Department of Pathophysiology,Shanghai Jiao Tong University School of Medicine
    Presenting Author: Zimei Shu – Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine
    Co-Author: Jinsong Duan – State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China.
    Co-Author: Jiawei Wang – State Key Laboratory of Membrane Biology, Beijing Frontier Research Center for Biological Structure, School of Life Sciences, Tsinghua University, Beijing 100084, China
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0812 - Partial GPVI depletion protects against arterial thrombosis in vivo by inhibiting platelet procoagulant activity without worsening the aspirin-associated bleeding risk.
    Room: Exhibition Hall
    Presenting Author: Stefano Navarro, PhD – Universitätklinikum Würzburg
    Co-Author: Sarah Beck – Universitätklinikum Würzburg
    Co-Author: Marijke Kuijpers – Maastricht University
    Co-Author: Johan Heemskerk – Synapse Research Institute Maastricht
    Co-Author: David Stegner – Institute for Experimental Biomedicine, University Hospital Würzburg
    Co-Author: Bernhard Nieswandt – University Hospital Würzburg
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0815 - Mechanism of Bile acid in regulating platelet function and thrombotic diseases
    Room: Exhibition Hall
    Co-Author: Xianghui Zhou – Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
    Co-Author: Xin Zhou – Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
    Co-Author: Zhao Zhang – Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
    Presenting Author: Zhipeng Cheng – Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
    Co-Author: Yu Hu – Institution of Hematology, Wuhan Union Hospital, Tongji medical college, Huazhong University of Science and Technology
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0816 - Generation of new Affimers that modulate platelet GPVI-ligand interactions and selectively target GPVI dimer
    Room: Exhibition Hall
    Presenting Author: Rui-Gang Xu, PhD – University of Leeds
    Co-Author: Christian Tiede – University of Leeds
    Co-Author: Antonio N. Calabrese – University of Leeds
    Co-Author: Lih T. Cheah, PhD – University of Leeds
    Co-Author: Thomas L. Adams – University of Leeds
    Co-Author: Julia S. Gauer, PhD – University of Leeds
    Co-Author: Matthew S. Hindle – Leeds Beckett University
    Co-Author: Alexandre Slater – University of Birmingham
    Co-Author: Cédric Duval, PhD – University of Leeds
    Co-Author: Khalid M. Naseem – University of Leeds
    Co-Author: Andrew B. Herr – Cincinnati Children's Hospital
    Co-Author: Darren C. Tomlinson – University of leeds
    Co-Author: Steve P. Watson – University of Birmingham
    Co-Author: Robert A. S. Ariëns – University of Leeds
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0817 - Visualising the dynamics of movement of GPVI and CLEC-2 upon ligand engagement
    Room: Exhibition Hall
    Presenting Author: Joanne Clark, PhD – University of Birmingham
    Co-Author: Zsombor Koszegi – University of Birmingham
    Co-Author: Eleyna Martin – University of Birmingham
    Co-Author: Davide Calebiro – University of Birmingham
    Co-Author: Steve P. Watson – University of Birmingham
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0818 - Structure and function studies of the receptor-type protein tyrosine phosphatase CD148
    Room: Exhibition Hall
    Presenting Author: Lina El Badaoui – University of Westminster
    Co-Author: Alastair Barr – University of Westminster
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0820 - Decreased clot size following stasis and modulated platelet-derived ROS in GPVI deficiency
    Room: Exhibition Hall
    Presenting Author: Julia S. Gauer, PhD – University of Leeds
    Co-Author: Helen R. McPherson – University of Leeds
    Co-Author: Amanda D. V. MacCannell – University of Leeds
    Co-Author: Lee D. Roberts – University of Leeds
    Co-Author: Cédric Duval, PhD – University of Leeds
    Co-Author: Robert A. S. Ariëns – University of Leeds
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0822 - The antiplatelet and antithrombotic effects of UDCA as a TREM2 agonist
    Room: Exhibition Hall
    Co-Author: Yulong Zhang, MD – School of Pharmacy, Tianjin Medical University, Tianjin, China
    Presenting Author: Xiaowen Wu, MA – School of Pharmacy, Tianjin Medical University, Tianjin, China
    Co-Author: Qian Liu – School of Pharmacy, Tianjin Medical University
    Co-Author: Meng Du – School of Pharmacy, Tianjin Medical University
    Co-Author: Yixian Wang – School of Pharmacy, Tianjin Medical University
    Co-Author: Meina Jin – School of Pharmacy, Tianjin Medical University
    Co-Author: Qingyuan Yang – School of Pharmacy, Tianjin Medical University
    Co-Author: Guanxing Pan – Department of Pharmacy, The First Affiliated Hospital of Fujian Medical University
    Co-Author: Zhongren Ding – School of Pharmacy, Tianjin Medical University; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences , Fudan University; Department of Geriatrics, The Second Hospital of Tianjin Medical University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0823 - Development and optimisation of a novel 9-parameter flow cytometry panel for human platelet phenotyping
    Room: Exhibition Hall
    Presenting Author: Daisie M. Yates – University of Leeds
    Co-Author: Ann W. Morgan – University of Leeds/NHS
    Co-Author: Khalid M. Naseem – University of Leeds
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0824 - BTKi of Varying Specificity are Potent Inhibitors of Platelet ITAM Signaling Pathways
    Room: Exhibition Hall
    Presenting Author: Thomas Kartika, MD – Rockefeller University/Weill-Cornell
    Co-Author: Lorena Buitrago – Rockefeller University
    Co-Author: Barry Coller – Rockefeller University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0826 - Broccoli sulforaphane potentiates prostaglandins on preventing human platelet aggregation
    Room: Exhibition Hall
    Presenting Author: CHIN-CHUNG WU, PhD – Kaohsiung Medical University
    Co-Author: Yi-Hsuan Yang – Kaohsiung Medical University
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    13:45 – 14:45 ICT
    PB0827 - Flavonoid-rich plant extracts inhibit platelet aggregation induced by different reagents
    Room: Exhibition Hall
    Co-Author: Dezso Csupor – Institute of Clinical Pharmacy, University of Szeged
    Presenting Author: Istvan Takacs, PhD – Diagon GmbH
    Co-Author: Aron Hauler – Diagon GmbH
    Co-Author: Nanett Mokran – Diagon GmbH
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    14:45 – 15:00 ICT
    OC 48.1 - Vps34 localizes to the nucleolus and mediates megakaryocyte maturation via ribosome biogenesis
    Room: 211 A-D
    Co-Author: Ivana Bertovic – University of Rijeka, Faculty of Biotechnology and Drug Development
    Co-Author: Sladana Bursac – University of Rijeka, Faculty of Medicine, Department of Molecular Medicine and Biotechnology
    Co-Author: Sinisa Volarevic – University of Rijeka, Faculty of Medicine, Department of Molecular Medicine and Biotechnology
    Presenting Author: Antonija Jurak Begonja, PhD – University of Rijeka, Faculty of Biotechnology and Drug Development
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    15:00 – 15:15 ICT
    OC 48.2 - Aging-Related Changes in Megakaryocyte Progenitors: Single-Cell Transcriptomics Study
    Room: 211 A-D
    Presenting Author: Pratintip Lee, MD – Center for Molecular Cardiology, University of Zurich, Cantonal Hospital Baden, Switzerland
    Co-Author: Soheil Saeedi Saravi – Center for Translational and Experimental Cardiology, University Hospital Zurich
    Co-Author: Meret Allemann – Center for Molecular Cardiology, University of Zurich, Cantonal Hospital Baden, Switzerland
    Co-Author: Carolina Balbi – Center for Molecular Cardiology, University of Zurich, Cantonal Hospital Baden, Switzerland
    Co-Author: Tongtong Wang – Institute of Food, Nutrition and Health, ETH Zurich
    Co-Author: Christian Wolfrum – Institute of Food, Nutrition and Health, ETH Zurich
    Co-Author: Jürg Hans Beer – Center for Molecular Cardiology, University of Zurich, Cantonal Hospital Baden, Switzerland
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    15:15 – 15:30 ICT
    OC 48.3 - Contractility of iPSC-derived megakaryocyte precursors at different stages of development
    Room: 211 A-D
    Co-Author: Oleg V. Kim – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Co-Author: Rustem I. Litvinov – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Co-Author: Deborah L. French – Department of Pathology and Laboratory Medicine, The Children’s Hospital of Philadelphia
    Co-Author: Lawrence F. Brass – Department of Hematology and Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Presenting Author: John W. Weisel – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    15:30 – 15:45 ICT
    OC 48.4 - Loss of PP1β leads to abnormal megakaryocyte development, severe thrombocytopenia, osteosclerosis and myelofibrosis
    Room: 211 A-D
    Presenting Author: Gabriel H. M Araujo – University Hospital Würzburg
    Co-Author: Maximilian Englert – University Hospital Würzburg
    Co-Author: Audrey Chang – UT Southwestern Medical Center
    Co-Author: Angus Nairn – Yale School of Medicine
    Co-Author: Bernhard Nieswandt – University Hospital Würzburg
    Co-Author: Zoltan Nagy, PhD – University Hospital Würzburg
    Platelets and Megakaryocytes
  • Monday, Jun 24th
    15:45 – 16:00 ICT
    OC 48.5 - Crucial role of casein kinase 1α in megakaryocyte cytoskeletal rearrangements and thrombopoiesis
    Room: 211 A-D
    Presenting Author: Ferdinand Kollotzek, M. Sc. – Department of Cardiology and Angiology, University of Tuebingen
    Co-Author: Melina Fischer, MSc – Department of Cardiology and Angiology, University of Tuebingen
    Co-Author: Patrick Münzer – Department of Cardiology and Angiology, University of Tuebingen
    Co-Author: Mailin-Christin Manke – Department of Cardiology and Angiology, University of Tuebingen
    Co-Author: Vanessa Göb – 5Institute for Experimental Biomedicine, University Hospital Würzburg
    Co-Author: Kristina Mott – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany
    Co-Author: Irene Gonzalez Menendez – Institute of Pathology, University of Tübingen, Germany
    Co-Author: Leticia Quintanilla de Fend – Institute of Pathology, University of Tübingen, Germany
    Co-Author: Andreas Mack – Institute of Anatomy, University of Tübingen, Germany
    Co-Author: Harald Schulze – University Hospital Würzburg, Department of Experimental Biomedicine I, Würzburg, Germany
    Co-Author: David Stegner – Institute for Experimental Biomedicine, University Hospital Würzburg
    Co-Author: Robert Ahrends – Department of Analytical Chemistry, University of Vienna, Austria
    Co-Author: Oliver Borst – Department of Cardiology and Angiology, University of Tuebingen
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    08:00 – 08:20 ICT
    SOA 20.1 - Interactions of platelet protein kinase signaling in response to ITAM-linked receptors
    Room: Ballroom B4
    Speaker: Kerstin Jurk, PhD – Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg University, Mainz, Germany
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    08:25 – 08:45 ICT
    SOA 20.2 - GPIb-IX-V structure and signaling
    Room: Ballroom B4
    Speaker: Renhao Li, PhD – First Affiliated Hospital, Zhejiang University School of Medicine
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    08:50 – 09:10 ICT
    SOA 20.3 - Recent insights in platelet signaling
    Room: Ballroom B4
    Speaker: Amanda J. Unsworth, DPhil – Manchester Metropolitan University
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    11:15 – 12:00 ICT
    PL 04.1 - GPVI: Cloning to the clinic
    Room: Plenary Hall
    Speaker: Martine Jandrot-Perrus, MD., PhD. – Laboratory for Vascular Translational Science, UMR_S1148 INSERM, University Paris Cité, Hôpital Bichat, Paris, France
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    12:15 – 13:00 ICT
    MC 23.1 - Platelet production in vitro
    Room: 107A
    Speaker: Alessandra Balduini, MD – University of Pavia, Pavia, Italy
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    14:45 – 15:00 ICT
    OC 68.1 - Discovery of piezo1 as a mediator of mechanotransduction in platelets
    Room: 211 A-D
    Co-Author: Arif s/o Abdul Jabbar – Cambridge University
    Co-Author: Suman Guntupalli – Cleveland Clinic
    Co-Author: Rohan Bhandari – Cleveland Clinic
    Co-Author: Anu Aggarwal – Cleveland Clinic
    Co-Author: Matthew Godwin – Cleveland Clinic
    Co-Author: Mariya Ali – Cleveland Clinic
    Co-Author: Edelyn Huijun Park – Cleveland Clinic
    Co-Author: Reina Samuel – Cleveland Clinic
    Presenting Author: Scott J. Cameron, PhD, MD – Cleveland Clinic
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    15:00 – 15:15 ICT
    OC 68.2 - SLFN14 deletion causes macrothrombocytopenia and thrombus instability by dysregulating ubiquitination and degradation pathways in platelets and megakaryocytes.
    Room: 211 A-D
    Presenting Author: Neil V. Morgan, PhD – University of Birmingham
    Co-Author: Xenia Sawkulycz – University of Birmingham
    Co-Author: Rachel Stapley – University of Birmingham
    Co-Author: Lourdes Garcia Quintanilla – University of Birmingham
    Co-Author: Amna Ahmed – University of Birmingham
    Co-Author: Elizabeth Haining – University of Birmingham
    Co-Author: Nayandeep Kaur – University of Birmingham
    Co-Author: Andrea Bacon – University of Birmingham
    Co-Author: Dean Kavanagh – University of Birmingham
    Co-Author: Natalie Poulter – University of Birmingham
    Co-Author: Julie Rayes, PhD – University of Birmingham
    Co-Author: Steve Thomas – University of Birmingham
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    15:15 – 15:30 ICT
    OC 68.3 - FLI-1 variants reduce TALIN1 expression in human megakaryocytes and platelets
    Room: 211 A-D
    Presenting Author: ELISA GABINAUD, Master's degree – C2VN
    Co-Author: Laurent Hannouche – C2VN
    Co-Author: Mathilde Veneziano Broccia – C2VN
    Co-Author: Timothée Bigot – C2VN
    Co-Author: Elisa Andersen – C2VN
    Co-Author: Paul Saultier – hospital APHM
    Co-Author: Manal IBRAHIM – Biologic Hematology, hospital APHM, Marseille
    Co-Author: Justine SUFFIT – C2VN
    Co-Author: Anne Bauters – CHU Lille, Service d'Hemostase et Transfusion - Lille FRANCE
    Co-Author: Anne Vincenot – CHU Paris Robert Debré, Paris, France
    Co-Author: Marie-Christine ALESSI – Aix Marseille Univ, Inserm 1263, inrae 1260, C2VN, APHM
    Co-Author: Marjorie POGGI – AMU
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    15:30 – 15:45 ICT
    OC 68.4 - Transmembrane TMX1 counterbalances the effect of ERp46 to inhibit platelet activation
    Room: 211 A-D
    Presenting Author: Zhenzhen Zhao, MD – Soochow Universtiy
    Co-Author: yixin cheng – National Clinical Research Center for Hematologic Diseases,Soochow University
    Co-Author: meinan peng – Soochow University
    Co-Author: yuxin zhang – National Clinical Research Center for Hematologic Diseases, Cyrus Tang Medical Institute,Soochow University
    Co-Author: Shuo Liu – Soochow University
    Co-Author: Yaowei Sun – Soochow Universtiy
    Co-Author: Yue han – National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, First Affiliated Hospital of Soochow University
    Co-Author: Depei Wu – The First Affiliated Hospital of Soochow University
    Co-Author: Aizhen Yang, PhD – The Cyrus Tang Hematology Center, Soochow University
    Platelets and Megakaryocytes
  • Tuesday, Jun 25th
    15:45 – 16:00 ICT
    OC 68.5 - Platelet Drp1 phosphorylation is controlled by a dual phosphorylation pathway requiring dense granule release: Implications for evaluating antiplatelet therapy
    Room: 211 A-D
    Co-Author: David A. Barrios – PlateletDiagnostics, LLC
    Co-Author: Secil Koseoglu – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Shihui Guo – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Sabrina Zerbey – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Matthew Powers – PlateletDiagnostics
    Co-Author: Arielle Urman – Beth Israel Deaconess Medical Center
    Co-Author: Somal Khan – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Dominick Svrcek – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Haley Clark – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Rushad Patell, MBBS – Beth Israel Deaconess Medical Center
    Co-Author: Jeffrey I. Zwicker, MD – Hematology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Presenting Author: Robert Flaumenhaft, MD, PhD – BIDMC/Harvard Medical School
    Platelets and Megakaryocytes
  • Wednesday, Jun 26th
    10:15 – 10:30 ICT
    OC 78.1 - Harnessing the co-inhibitory receptor G6b-B using cis-acting platelet receptor inhibitors (CAPRIs)
    Room: 208 A-D
    Co-Author: Alexandra Mazharian – Inserm UMRS 1255
    Presenting Author: Ophélie Bertin, MSc – University of Strasbourg, Inserm UMR_S1255,
    Co-Author: Johanna Augros – Inserm UMR1327
    Co-Author: Alicia bornert – Inserm UMRS-1255
    Co-Author: Cécile Loubiere – Inserm UMRS-1255
    Co-Author: Friederike Jönsson – Institut Pasteur, Inserm UMR1222
    Co-Author: Jérôme Rollin – Inserm UMR1327, University of Tours
    Co-Author: Yotis Senis – Inserm UMRS-1255
    Platelets and Megakaryocytes
  • Wednesday, Jun 26th
    10:30 – 10:45 ICT
    OC 78.2 - Platelet-specific deletion of CK2α results in a robust protection against arterial thrombosis and beneficial myocardial recovery after I/R injury
    Room: 208 A-D
    Co-Author: Mailin-Christin Manke – Department of Cardiology and Angiology, University of Tuebingen
    Presenting Author: Melina Fischer, MSc – Department of Cardiology and Angiology, University of Tuebingen
    Co-Author: Ferdinand Kollotzek, M. Sc. – Department of Cardiology and Angiology, University of Tuebingen
    Co-Author: Jan Philipp Schütte – Department of Cardiology and Angiology, University of Tuebingen
    Co-Author: Patrick Münzer – Department of Cardiology and Angiology, University of Tuebingen
    Co-Author: Oliver Borst – Department of Cardiology and Angiology, University of Tuebingen
    Platelets and Megakaryocytes
  • Wednesday, Jun 26th
    10:45 – 11:00 ICT
    OC 78.3 - Generation and characterization of inactive Spleen tyrosine kinase mice; Evaluation of ITAM and hemITAM signaling and function in platelets
    Room: 208 A-D
    Co-Author: Carol Dangelmaier – Temple University School of Medicine
    Co-Author: Dhruv Vajipayajula – Temple University School of Medicine
    Co-Author: Monica Wright – Temple University School of Medicine
    Co-Author: Alexander Tsygankov – Temple University School of Medicine
    Presenting Author: Satya P. Kunapuli, PhD – Lewis Katz Temple University School of Medicine
    Platelets and Megakaryocytes
  • Wednesday, Jun 26th
    11:00 – 11:15 ICT
    OC 78.4 - GRK3 regulates platelet function through general G protein-coupled receptor desensitization
    Room: 208 A-D
    Co-Author: SACHIN UPADHAYAYA – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Presenting Author: PREETI KUMARI CHAUDHARY, PhD – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Co-Author: SANGGU KIM – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Co-Author: SOOCHONG KIM – Laboratory of Veterinary Pathology and Platelet Signaling, College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea
    Platelets and Megakaryocytes
  • Wednesday, Jun 26th
    11:15 – 11:30 ICT
    OC 78.5 - G6b-B controls transcription factor expression during megakaryocyte maturation
    Room: 208 A-D
    Presenting Author: Zoltan Nagy, PhD – University Hospital Würzburg
    Co-Author: Maximilian Englert – University Hospital Würzburg
    Co-Author: Bernhard Nieswandt – University Hospital Würzburg
    Platelets and Megakaryocytes