Skip to main content


  • Saturday, Jun 22nd
    13:00 – 13:15 ICT
    OC 07.1 - The clearance receptor CLEC4M regulates plasma factor V levels through factor V binding and internalization
    Room: 210 A-D
    Presenting Author: Adarsh K. Mohapatra, MSc – Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, Netherlands
    Co-Author: Pierre Morange, MD, PhD – Aix-Marseille University
    Co-Author: Elisabetta Castoldi – Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, Netherlands
    Co-Author: Franck Peiretti – C2VN, INRAE, INSERM Aix-Marseille University, Marseille, France
    Coagulation Factors and Co-Factors
  • Saturday, Jun 22nd
    13:15 – 13:30 ICT
    OC 07.2 - Engineering a membrane-independent human prothrombinase through parsimonious mutation of factor Xa
    Room: 210 A-D
    Presenting Author: Fatma Isik Ustok, PhD – University of Cambridge
    Co-Author: James A. Huntington, PhD – University of Cambridge
    Coagulation Factors and Co-Factors
  • Saturday, Jun 22nd
    13:30 – 13:45 ICT
    OC 07.3 - Structural basis of prothrombin recognition by a Type-I anti-prothrombin antiphospholipid antibody revealed by cryo-EM.
    Room: 210 A-D
    Presenting Author: Suresh Kumar, PhD – Saint Louis University School of Medicine
    Co-Author: Vittorio Pengo – Department of Cardiac-Thoracic-Vascular Sciences and Public Health University of Padova
    Co-Author: Robert Flaumenhaft, MD, PhD – BIDMC/Harvard Medical School
    Co-Author: Nicola Pozzi – Saint Louis University School of Medicine
    Coagulation Factors and Co-Factors
  • Saturday, Jun 22nd
    13:45 – 14:00 ICT
    OC 07.4 - Structural biology of substrate recognition by tissue factor/factor VIIa
    Room: 210 A-D
    Presenting Author: Josepha C. Sedzro, PhD – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: Fabienne Birkle – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Co-Author: Katarina Meze – Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
    Co-Author: Amanda Photenhauer – Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
    Co-Author: Xueyuan Peng – Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
    Co-Author: Melanie P. Muller – Department of Biochemistry, Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA
    Co-Author: Sarah Kearns – Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
    Co-Author: Michael A. Cianfrocco – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA, Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA
    Co-Author: Emad Tajkhorshid – Department of Biochemistry, Center for Biophysics and Quantitative Biology, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA
    Co-Author: Melanie D. Ohi – Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA, Department of Cell and Developmental Biology, University of Michigan School of Medicine, Ann Arbor, MI, USA
    Co-Author: James H. Morrissey – Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, USA
    Coagulation Factors and Co-Factors
  • Saturday, Jun 22nd
    14:00 – 14:15 ICT
    OC 07.5 - A 3.3Å cryo-EM structure of an engineered high-affinity human prothrombinase complex
    Room: 210 A-D
    Co-Author: Fatma Isik Ustok, PhD – University of Cambridge
    Co-Author: Alexandre Faille – University of Cambridge
    Presenting Author: James A. Huntington, PhD – University of Cambridge
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    08:00 – 08:20 ICT
    SOA 01.1 - Factor IXa zymogen variants for improved hemostasis
    Room: 110 A-C
    Speaker: Lacramioara Ivanciu, PhD – University of Pennsylvania / Children's Hospital of Philadelphia
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    08:25 – 08:45 ICT
    SOA 01.2 - Novel structures and ligand complexes of coagulation factor XII
    Room: 110 A-C
    Speaker: David Gailani, MD – Vanderbilt University Medical Center
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    08:50 – 09:10 ICT
    SOA 01.3 - Exosite crosstalk in thrombin
    Room: 110 A-C
    Speaker: James C. Fredenburgh, PhD – McMaster University | Thrombosis and Atherosclerosis Research Institute (TaARI)
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    09:45 – 10:00 ICT
    LB 01.2 - Engineering FVIII protein for enhancing expression and secretion profile to achieve normal level of FVIII in plasma utilizing noninvasive transcutaneous ultrasound mediated gene delivery.
    Room: Plenary Hall
    Presenting Author: Ivan Krivega, PhD – SonoThera
    Co-Author: Ivan Krivega – SonoThera
    Co-Author: Julia Poniatowski – Sonothera
    Co-Author: David Kim – SonoThera
    Co-Author: Elizabeth Del Greco – SonoThera
    Co-Author: Surabhi Rao – SonoThera
    Co-Author: Victor Foster – SonoThera
    Co-Author: Bert Frederich – SonoThera
    Co-Author: Barry Campbell – SonoThera
    Co-Author: Adel Alonso – SonoThera
    Co-Author: Glenda Arauz – SonoThera
    Co-Author: Celia Ortiz – SonoThera
    Co-Author: Oliver Chen – SonoThera
    Co-Author: Dhruv Bole – SonoThera
    Co-Author: Katie Benthal – SonoThera
    Co-Author: Anagha Rao – SonoThera
    Co-Author: David Satyadi – SonoThera
    Co-Author: Zoya Gluzman-Poltorak – SonoThera
    Co-Author: Steve Feinstein – SonoThera
    Co-Author: Kenneth Greenberg – SonoThera
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    14:45 – 15:00 ICT
    OC 25.1 - Thiol isomerase ERp46 catalyzes the disulfide formation of coagulation factor XII enhancing its activation
    Room: 110 A-C
    Presenting Author: Aizhen Yang, PhD – The Cyrus Tang Hematology Center, Soochow University
    Co-Author: Yaqiong Zhang – Soochow Universtiy
    Co-Author: Yaowei Sun – Soochow Universtiy
    Co-Author: Zhenzhen Zhao, MD – Soochow Universtiy
    Co-Author: Zhipu Luo – Soochow Universtiy
    Co-Author: Yue Han – The First Affiliated Hospital of Soochow University
    Co-Author: Depei Wu – The First Affiliated Hospital of Soochow University
    Co-Author: Yi Wu, MD, PhD – Soochow University
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    15:00 – 15:15 ICT
    OC 25.2 - Amyloid fibrils trigger plasma clotting by activating the intrinsic pathway of blood coagulation and can explain intracardiac thrombosis in Transthyretin (ATTR) and Ig-Light Chain Amyloidosis (AL)
    Room: 110 A-C
    Presenting Author: Alessia Dei Rossi – Dept. of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy
    Co-Author: Laura Acquasaliente – Dept. of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy
    Co-Author: Ornella Leone – IRCCS University Hospital of Bologna, Bologna, Italy
    Co-Author: Serena Toffanin – Università di Padova
    Co-Author: Paolo Simioni, MD, PhD – University of Padova, Padova University Hospital
    Co-Author: Vincenzo De Filippis – Dept. of Pharmaceutical and Pharmacological Sciences, University of Padua, Padua, Italy
    Co-Author: Guglielmo Verona – Center for Amyloidosis, University College London, London, United Kingdom
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    15:15 – 15:30 ICT
    OC 25.3 - The Acinetobacter baumannii Secreted Protease CpaA Inhibits Factor XII-mediated Neutrophil Activation
    Room: 110 A-C
    Presenting Author: Dillon Bohinc – Case Western Reserve University
    Co-Author: Kara Bane – Case Western Reserve University
    Co-Author: Kris Blair – Fred Hutch/University of Washington/Seattle Children’s Cancer Consortium
    Co-Author: Eduarda Grinsztejn – Medicine Service, Section of Hematology-Oncology, Louis Stokes Veterans Administration Medical Center
    Co-Author: Steven Marshall – 5Research Service, Louis Stokes Cleveland Department of Veterans Affairs Medical Center
    Co-Author: Robert Bonomo – Department of Medicine, Division of Infectious Diseases, Case Western Reserve University School of Medicine,
    Co-Author: Daniel Lawrence – Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical School
    Co-Author: Maria Sandkvist – 1Department of Microbiology and Immunology, University of Michigan Medical School
    Co-Author: Evi X. Stavrou, MD – Department of Medicine, Hematology and Oncology Division, Case Western Reserve University (CWRU) School of Medicine
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    15:30 – 15:45 ICT
    OC 25.4 - Coagulation factor XI contributes to vascular dysfunction and cardiac inflammation in ischemia/reperfusion injury in mice with excess neurohormonal activation
    Room: 110 A-C
    Co-Author: Qi Luo – Medical Center of Mainz University
    Co-Author: Melania Aluia – Medical center of Mainz university
    Co-Author: Michael Molitor – Medical center of Mainz university
    Presenting Author: Phillip Wenzel, Professor, MD – University Medical Center Mainz
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    15:45 – 16:00 ICT
    OC 25.5 - Characterization of Interactions Between Skeletal Muscle Myosin and Activated Factor XI
    Room: 110 A-C
    Presenting Author: Chih-Jen Yang, MD – Oregon Health & Science University
    Co-Author: John Griffin – The Scripps Research Institute
    Co-Author: Hiroshi Deguchi – The Scripps Research Institute
    Co-Author: David Gailani, MD – Vanderbilt University Medical Center
    Co-Author: Owen McCarty – Oregon Health & Science University
    Co-Author: Cristina Puy – Oregon health & science university
    Coagulation Factors and Co-Factors
  • Sunday, Jun 23rd
    18:45 – 19:30 ICT
    MC 10.1 - How do natural anticoagulants harness coagulation initiation and thrombosis?
    Room: 206B
    Speaker: Tilman M. Hackeng, PhD – Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University
    Coagulation Factors and Co-Factors
  • Monday, Jun 24th
    11:15 – 12:00 ICT
    PL 03.1 - Exploring the thrombus niche: Lessons learned and therapeutic opportunities
    Room: Plenary Hall
    Speaker: John W. Weisel – Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Coagulation Factors and Co-Factors
  • Monday, Jun 24th
    14:45 – 15:00 ICT
    OC 49.1 - Arginine Methylation by Protein arginine methyltransferase 1 (PRMT1) on ADAMTS13 Affects Its Secretion and Proteolytic Activity
    Room: 208 A-D
    Presenting Author: Szumam Liu, PhD – University of Kansas Medical Center
    Co-Author: Xinyang Zhao – University of Kansas Medical Center
    Co-Author: Long Zheng, MD, PhD – University of Kansas Medical Center
    Coagulation Factors and Co-Factors
  • Monday, Jun 24th
    15:00 – 15:15 ICT
    OC 49.2 - Identification of structural elements in factor V and factor VIII that determine their routes in the early secretory pathway
    Room: 208 A-D
    Presenting Author: Bin Zhang, PhD – Cleveland Clinic Lerner Research Institute
    Co-Author: Yuan Zhang – Cleveland Clinic Lerner Research Institute
    Coagulation Factors and Co-Factors
  • Monday, Jun 24th
    15:15 – 15:30 ICT
    OC 49.3 - Influence of coagulation proteases on cognitive function
    Room: 208 A-D
    Presenting Author: Silke Zimmermann, MD PhD – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital; Leipzig, Germany
    Co-Author: Akash Mathew – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital; Leipzig, Germany
    Co-Author: Gyulten Mangova – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital; Leipzig, Germany
    Co-Author: Berend Isermann, Prof. Dr. med. – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany
    Coagulation Factors and Co-Factors
  • Monday, Jun 24th
    15:30 – 15:45 ICT
    OC 49.4 - An effective and safe strategy for anti-thrombosis therapy by monoclonal antibody blocking the interaction of FIXa with FVIIIa
    Room: 208 A-D
    Presenting Author: Xuemei Fan, PhD – Shanghai Jiao Tong University School of Medicine
    Co-Author: Junling Liu, PhD – Shanghai Jiao Tong University School of Medicine
    Co-Author: Lin Zhang – Shanghai Jiao Tong University
    Co-Author: Xueqing Sun – Shanghai jiao tong university
    Co-Author: Yanhua Wang – Shanghai synvida bio.tech
    Co-Author: Yanjun Liu – Shanghai synvida biotech
    Co-Author: Qingqin Lai – Shanghai synvida biotech
    Coagulation Factors and Co-Factors
  • Monday, Jun 24th
    15:45 – 16:00 ICT
    OC 49.5 - FVIII mutated with D519V/E665V/K1813A enhances coagulation potentials by high affinity for FIXa and stabilizing A2 domain
    Room: 208 A-D
    Presenting Author: Yuto Nakajima, Md.PhD – Department of Pediatrics
    Co-Author: Akihisa Oda – Department of Pediatrics
    Co-Author: Keiji Nogami – Nara Medical University, Nara, Japan
    Coagulation Factors and Co-Factors
  • Monday, Jun 24th
    18:45 – 19:30 ICT
    MC 19.1 - Clinical observations in out-of-check contact activation
    Room: 206A
    Speaker: Remy S. Petersen, MD – Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    08:00 – 08:20 ICT
    SOA 19.1 - Biophysical approaches in understanding the antiphospholipid syndrome
    Room: 110 A-C
    Speaker: Nicola Pozzi – Saint Louis University School of Medicine
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    08:25 – 08:45 ICT
    SOA 19.2 - AI tools to interrogate genetics of coagulation factors
    Room: 110 A-C
    Speaker: Rosanna Asselta, PhD – Humanitas University
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    08:50 – 09:10 ICT
    SOA 19.3 - Structural bioinformatics technologies for rational drug design: From In Silico to In Vivo
    Room: 110 A-C
    Speaker: Kanin Wichapong, PhD – Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    10:00 – 10:15 ICT
    OC 59.3 - A Novel Mechanism Mediated by Allosteric Disulfide Bonds Fine-Tunes Thrombus Formation
    Room: 208 A-D
    Presenting Author: Keyu Lv, phD – Huazhong University of Science and Technology
    Co-Author: Shuai Chen – Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology
    Co-Author: Xulin Xu – Department of Pharmacology, School of Basic Medicine, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology
    Co-Author: Joyce Chiu – The Centenary Institute, University of Sydney
    Co-Author: Haoqing J. Wang – School of Biomedical Engineering, Faculty of Engineering, The University of Sydney
    Co-Author: Yunyun Han – Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology
    Co-Author: Xiaodan Yang – Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology
    Co-Author: Sheryl R Bowley – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School
    Co-Author: Zhaoming Tang, MD – Department of Clinical Laboratory, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
    Co-Author: Ning Tang, MPH – Tongji hospital, Tongji Medical College, Huazhong University of Science and Technology
    Co-Author: Aizhen Yang, PhD – The Cyrus Tang Hematology Center, Soochow University
    Co-Author: Yi Wu, MD, PhD – Soochow University
    Co-Author: Lining A. Ju, PhD – University of Sydney
    Co-Author: Alvin H. Schmaier – Department of Medicine, University Hospitals Cleveland Medical Center and Case Western Reserve University
    Co-Author: Philip Hogg, BSc(Hon), PhD – University of Technology Sydney and Centenary Institute
    Co-Author: Chao Fang, PhD – Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1076 - Reduction of plasma kallikrein by in vivo CRISPR-based gene editing of KLKB1 does not alter coagulation in patients with hereditary angioedema
    Room: Exhibition Hall
    Presenting Author: Remy S. Petersen, MD – Department of Vascular Medicine, Amsterdam Cardiovascular Sciences, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands
    Co-Author: Danny M. Cohn – Amsterdam University Medical Center, Amsterdam, the Netherlands
    Co-Author: Padmalal Gurugama – Cambridge University Hospitals, NHS Foundation Trust
    Co-Author: Karen Lindsay – Te Whatu Ora/Te Toka Tumai, Auckland, New Zealand
    Co-Author: Lauré M. Fijen – Amsterdam University Medical Center, Amsterdam, the Netherlands
    Co-Author: Adele Golden – Intellia Therapeutics, Cambridge, MA, USA
    Co-Author: Carri Boiselle – Intellia Therapeutics
    Co-Author: Yuanxin Xu – Intellia Therapeutics, Cambridge, MA, USA
    Co-Author: James Butler – Intellia Therapeutics, Cambridge, MA, USA
    Co-Author: Mrinal Y. Shah – Intellia Therapeutics, Cambridge, MA, USA
    Co-Author: David Maag – Intellia Therapeutics
    Co-Author: Hilary Longhurst – Te Whatu Ora/Te Toka Tumai
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1077 - Factor XII-uPAR interaction drives oxidative DNA damage and senescence in kidney tubular cells under hyperglycemic conditions
    Room: Exhibition Hall
    Presenting Author: Ahmed Elwakiel – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany
    Co-Author: Rajiv Rana – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany
    Co-Author: Jayakumar Manoharan, M.Tech – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany
    Co-Author: Saira Ambreen, phd – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany
    Co-Author: Shrey Kohli, PhD – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany
    Co-Author: Khurrum Shahzad – University of Leipzig
    Co-Author: Thomas Renné – University Medical Center Hamburg-Eppendorf
    Co-Author: Berend Isermann, Prof. Dr. med. – Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, Leipzig University, Leipzig, Germany
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1078 - Links between coagulation signaling in viral infection and autoimmunity
    Room: Exhibition Hall
    Presenting Author: Kristin Grunz – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Germany
    Co-Author: Niels Lemmermann – University Hospital Bonn
    Co-Author: Nadine Müller-Calleja – Institute of Clinical Chemistry and Laboratory Medicine
    Co-Author: Wolfram Ruf – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1079 - Elevated plasma factor XI is associated with postthrombotic syndrome
    Room: Exhibition Hall
    Co-Author: Konrad Stępień – Department of Thromboembolic Disorders, Institute of Cardiology, Jagiellonian University Medical College
    Co-Author: Magdalena Kopytek – Krakow Centre for Medical Research and Technologies, John Paul II Hospital, Kraków, Poland
    Co-Author: Jakub Siudut – Krakow Centre for Medical Research and Technologies, St. John Paul II Hospital
    Co-Author: Jarosław Zalewski – Department of Coronary Artery Disease and Heart Failure, Institute of Cardiology, Jagiellonian University Medical College
    Presenting Author: Anetta Undas – Department of Thromboembolic Disorders, Institute of Cardiology, Jagiellonian University Medical College
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1080 - From clotting to calcification: Gla-domains as guardians of vascular remodeling
    Room: Exhibition Hall
    Co-Author: Stijn M. Agten – Department of BIochemistry, Maastricht University
    Co-Author: Dennis Suylen – Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University
    Co-Author: Anouk Gentier – Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University
    Co-Author: Leon J. Schurgers, PhD – Department of BIochemistry, Cardiovascular Research Institute Maastricht, Maastricht University
    Presenting Author: Tilman M. Hackeng, PhD – Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1081 - Endothelial-derived microvesicles promote pro-migratory cross-talk with smooth muscle cells by a mechanism requiring tissue factor and PAR2 activation
    Room: Exhibition Hall
    Co-Author: Sophie J. Featherby – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Presenting Author: Camille Ettelaie – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1082 - Intratumoral administration of anticoagulant Protein S reduces tumor volume in nude mouse model of pancreatic cancer.
    Room: Exhibition Hall
    Co-Author: Teagan M. Prouse – Louisiana State University Health Sciences Center, Department of Interdisciplinary Oncology
    Co-Author: Narender Kumar – LSUHSC
    Co-Author: Kristina Larter – LSUHSC, Department of Genetics
    Co-Author: Sonali Ghosh – LSUHSC
    Co-Author: Mohammad A. Mohammad – LSUHSC
    Co-Author: Samarpan Majumder – LSUHSC, Department of Genetics
    Presenting Author: Rinku Majumder – LSUHSC
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1083 - Development and characterization of novel nanoparticulate carrier for oral delivery of low molecular weight Heparin
    Room: Exhibition Hall
    Presenting Author: Saurabh Bhargava – United Institute of Pharmacy
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1084 - Long-term prophylaxis outcome in patients with prothrombin deficiency: A single center experience
    Room: Exhibition Hall
    Co-Author: Mehran karimi, MD. – Pediatric Hematology-Oncology department, American Hospital Dubai
    Presenting Author: Mohammadreza Bordbar, MD – Shiraz University of Medical Sciences
    Co-Author: Asghar Bazrafshan – Hematology Research Center, Shiraz university of Medical Sciences
    Co-Author: Hakimeh Tavoosi – Shiraz Hemophilia Comprehensive Center, Dastgheib Hospital, Shiraz University of Medical Sciences
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1085 - The histopathological landscape of synovitis in hemophilic arthropathy
    Room: Exhibition Hall
    Presenting Author: Roberta Gualtierotti, PhD – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy; Università degli Studi di Milano, Department of Pathophysiology and Transplantation, Milan, Italy
    Co-Author: Silvia Spena – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy
    Co-Author: Andrea Giachi – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center
    Co-Author: Chiara Suffritti – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center
    Co-Author: Sara Arcudi, MD, PhD – Foundation I.R.C.C.S. Ca’ Granda, Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy
    Co-Author: Alessandro Ciavarella – Fondazione IRCCS Ca’Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy
    Co-Author: Simona Maria Siboni – Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center
    Co-Author: Carlo Pescia – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Unit of Anatomic Pathology
    Co-Author: Umberto Gianelli – Università degli Studi di Milano, Department of Health Sciences, ASST Santi Paolo e Carlo, Anatomic Pathology unit
    Co-Author: Luigi Solimeno – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Division of Orthopaedic Surgery and Traumatology
    Co-Author: Flora Peyvandi, MD, PhD – Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Università degli Studi di Milano, Department of Pathophysiology and Transplantation
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1086 - Hemostatic protein profiles in urological tumors and plasma: Insights into tumor biology and thrombosis
    Room: Exhibition Hall
    Presenting Author: Julia Oto – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe
    Co-Author: Raquel Herranz – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe
    Co-Author: Emma Plana – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe
    Co-Author: Antonio Moscardó – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe
    Co-Author: Patricia Verger – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe
    Co-Author: María Castaño – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe
    Co-Author: Fernando Cana – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe
    Co-Author: César David Vera-Donoso – Urology Service, La Fe University and Polytechnic Hospital
    Co-Author: Pau Martínez-Rodríguez – Urology Service, Manises Hospital
    Co-Author: Manuel Martínez-Sarmiento – Urology Service, La Fe University and Polytechnic Hospital
    Co-Author: Santiago Bonanad – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Medical Research Institute Hospital La Fe
    Co-Author: John-Bjarne Hansen – Thrombosis Research Center (TREC), Department of Clinical Medicine, UiT - the Arctic University of Norway
    Co-Author: Pilar Medina, PhD – Haemostasis, Thrombosis, Arteriosclerosis and Vascular Biology Research Group, Health Research Institute Hospital La Fe
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1087 - Beyond bleeding: Exploring coagulation factors and cytokines in bone health in vitro
    Room: Exhibition Hall
    Presenting Author: Aline Bernar, MSc – Department of Pediatrics I, Medical University of Innsbruck, Austria
    Co-Author: Jennifer Gebetsberger – Department of Pediatrics I, Medical University of Innsbruck, Austria
    Co-Author: Monika Bauer – Department of Internal Medicine, Clinic II, Medical University of Innsbruck, Austria
    Co-Author: Michael Schirmer – Department of Internal Medicine, Clinic II, Medical University of Innsbruck, Austria
    Co-Author: Werner Streif – Department of Pediatrics I, Medical University of Innsbruck, Austria
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1088 - Association between coagulation and neurologic outcomes in acute ischemic stroke patients from the MR CLEAN NO-IV trial
    Room: Exhibition Hall
    Presenting Author: Angelique Ceulemans, MSc – Department of Neurology, Maastricht University Medical Center+, Maastricht, The Netherlands
    Co-Author: Wim H. van Zwam – Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, Maastricht, The Netherlands
    Co-Author: Robert J. van Oostenbrugge – Department of Neurology, Maastricht University Medical Center+, Maastricht, The Netherlands
    Co-Author: Moniek de Maat – Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands
    Co-Author: Charles B. L. M. Majoie – Department of Radiology and Nuclear Medicine, Amsterdam Neurosciences, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands
    Co-Author: Yvo B. W. E. M. Roos – Department of Neurology, Amsterdam UMC location University of Amsterdam, Amsterdam, The Netherlands
    Co-Author: Hugo ten Cate, MD, PHD – Departments of Internal Medicine and Biochemistry, Maastricht University Medical Center+, Maastricht, The Netherlands
    Co-Author: Henri M.H Spronk, PhD – Maastricht University
    Co-Author: Magdolna Nagy – Department of Biochemistry, Maastricht University Medical Center+, Maastricht, The Netherlands
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1089 - Neuronal recovery by Tissue factor signalling; A possible microvesicle-mediated mechanism for response to injury.
    Room: Exhibition Hall
    Co-Author: Sophie J. Featherby – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Presenting Author: Camille Ettelaie – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1090 - Procoagulant microvesicles released during injury and inflammation increase Tau and Amyloid Aβ42 metabolism
    Room: Exhibition Hall
    Co-Author: Sophie J. Featherby – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Presenting Author: Camille Ettelaie – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1091 - Tissue factor alters the expression of the epithelial-mesenchymal transition marker vimentin
    Room: Exhibition Hall
    Presenting Author: Sophie J. Featherby – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Co-Author: Farzana Haque – Division of Cancer, Hull-York Medical School, University of Hull, Cottingham Road, Hull, HU6 7RX, UK
    Co-Author: Anthony Maraveyas – Division of Cancer, Hull-York Medical School, University of Hull, Cottingham Road, Hull, HU6 7RX, UK
    Co-Author: Camille Ettelaie – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1092 - Performance evaluation and comparison of two diluted Russell viper venom time systems for lupus anticoagulant detection in systemic lupus erythematosus patients
    Room: Exhibition Hall
    Presenting Author: LI-CHUAN LAI, Master – Taichung Veterans General Hospital
    Co-Author: Hsien-Hsu Hsieh – Taichung Veterans General Hospital
    Co-Author: CHEN-YU LEE – Taichung Veterans General Hospital
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1093 - Clinical and Genetic Analysis of a inherit Factor Ⅻ Deficiency in China
    Room: Exhibition Hall
    Presenting Author: Donglei Zhang, MD – Department of Hematology, Zhongnan Hospital of Wuhan University
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1096 - Prolonged exposure of cells to exogenous tissue factor alters the regulations of G1/S checkpoint protein p16INKa
    Room: Exhibition Hall
    Presenting Author: Sophie J. Featherby – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Co-Author: Farzana Haque – Division of Cancer, Hull-York Medical School, University of Hull, Cottingham Road, Hull, HU6 7RX, UK
    Co-Author: Anthony Maraveyas – Division of Cancer, Hull-York Medical School, University of Hull, Cottingham Road, Hull, HU6 7RX, UK
    Co-Author: Camille Ettelaie – Hull-York Medical School/Biomedical Sciences, University of Hull, Cottingham Road, Hull, HU6 7RX.
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1097 - Salvianolic Acid B Inhibits Thrombosis and Directly Blocks the Thrombin Catalytic Site
    Room: Exhibition Hall
    Co-Author: Yiming Wang – The Hospital for Sick Children
    Co-Author: Miguel Neves – St. Michael's Hospital
    Co-Author: Tiffany Ni – St. Michael's Hospital
    Co-Author: Daniel Mackeigan – St. Michael's Hospital
    Co-Author: Aron Shoara – St. Michael's Hospital
    Co-Author: Xi Lei – St. Michael's Hospital
    Co-Author: Sladjana Slavkovic – St. Michael's Hospital
    Co-Author: Si-Yang Yu – St. Michael's Hospital
    Co-Author: Tyler Stratton – St. Michael's Hospital
    Co-Author: Reid Gallant – St. Michael's Hospital
    Co-Author: Dan Zhang – St. Michael's Hospital
    Co-Author: Xiaohong Xu – St. Michael's Hospital
    Co-Author: Cheryl Fernandes – St. Michael's Hospital
    Co-Author: Guangheng Zhu – St. Michael's Hospital
    Co-Author: Logan Donaldson – York University
    Co-Author: Philip Johnson – York University
    Co-Author: Kim Connelly – St. Michael's Hospital
    Co-Author: Margaret Rand – The Hospital for Sick Children
    Presenting Author: Heyu Ni, MD, PhD – University of Toronto / Canadian Blood Services
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1098 - Structural basis of von Willebrand factor multimerization and tubular storage
    Room: Exhibition Hall
    Presenting Author: Zimei Shu – Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine
    Co-Author: Jianwei Zeng – State Key Laboratory of Membrane Biology, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, China.
    Co-Author: Liang Liang – Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China;
    Co-Author: Aiwu Zhou – Department of Pathophysiology,Shanghai Jiao Tong University School of Medicine
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1099 - Mutation Ter462GlnextTer17 introduces a tail to C-terminus of protein C and causes venous thrombosis
    Room: Exhibition Hall
    Presenting Author: zhe lai, MA – shanghai ruijin hospital in China
    Co-Author: Yeling Lu – shanghai ruijin hospital in China
    Co-Author: Xiaohong Cai – ruijin hospital
    Co-Author: Jiaming Li – Department of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
    Co-Author: Shijie Zhou, MA – ruijin hospital
    Co-Author: Xi Wu, MD – Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Co-Author: Junwei Yuan, MA – Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Co-Author: Wenman Wu – Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
    Co-Author: Qiulan Ding – Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Co-Author: Xuefeng Wang – Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
    Co-Author: Jing Dai – Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1100 - Disulfide-bonded Forms of Prothrombin are Differentially Targeted by Anti-Prothrombin Antiphospholipid Antibodies
    Room: Exhibition Hall
    Presenting Author: Mark Schreuder, PhD – The Centenary Institute, University of Sydney
    Co-Author: Suresh Kumar, PhD – Saint Louis University School of Medicine
    Co-Author: Diego Butera – The Centenary Institute, University of Sydney
    Co-Author: Nicola Pozzi – Saint Louis University School of Medicine
    Co-Author: Philip J. Hogg – The Centenary Institute, University of Sydney
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1101 - Investigation of the reversal potential of engineered Factor Xa agents in apixaban and rivaroxaban treated plasma
    Room: Exhibition Hall
    Presenting Author: Wojciech Jankowski – US FDA
    Co-Author: Stepan Surov – US FDA
    Co-Author: Mikhail Ovanesov – US FDA
    Co-Author: Zuben Sauna – US FDA
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1102 - Covalently linked complexes of coagulation factor VIII and von Willebrand factor fragment display increased stability and half-life in animal models and retain their function.
    Room: Exhibition Hall
    Presenting Author: Barbara Solecka-Witulska – Octapharma Biopharmaceuticals GmbH, Molecular Biochemistry, Berlin, Germany
    Co-Author: Anna Postępska-Igielska – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Anna Svirina – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Katja Derkow – Octapharma Biopharmaceuticals GmbH, Molecular Biochemistry, Berlin, Germany
    Co-Author: Ulrike Noller – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Jessica Wernet – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Torsten Heidenreich – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Kirstin Rau – Octapharma Biopharmaceuticals GmbH, Molecular Biochemistry, Berlin, Germany
    Co-Author: Inga Frey – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Jennifer Ivlev – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Cathleen Wegmann – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Jana Zell – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Antra Zeltina – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Anja Brehm – Octapharma Biopharmaceuticals GmbH, Molecular Biochemistry, Berlin, Germany
    Co-Author: Silvio Wuschko – Octapharma Pharmazeutika Produktionsges.m.b.H., Vienna, Austria
    Co-Author: Sonja Werwitzke – Clinic of Haematology, Haemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
    Co-Author: Andreas Tiede, MD PhD – Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
    Co-Author: Thomas Güttler – Octapharma Biopharmaceuticals GmbH, Recombinant R&D, Heidelberg, Germany
    Co-Author: Guido Kohla – Octapharma Biopharmaceuticals GmbH, Molecular Biochemistry, Berlin, Germany
    Co-Author: Christoph Kannicht – Octapharma Biopharmaceuticals GmbH, Molecular Biochemistry, Berlin, Germany
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1103 - The association between high-density lipoprotein composition and hemostatic parameters in the Netherlands Epidemiology of Obesity (NEO) Study
    Room: Exhibition Hall
    Co-Author: Lushun Yuan – 1. Einthoven Laboratory for Vascular and Regenerative Medicine, Department of Internal Medicine, Nephrology, Leiden University Medical Center, Leiden, the Netherlands. 2. Department of Vascular Surgery, Intervention Center, Shanghai General Hospital, Shanghai Jiao Tong University, Shanghai, China.
    Presenting Author: Jihee Han – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: Renée de Mutsert – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: Frits R Rosendaal – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: Dennis O. Mook-Kanamori – 1. Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands. 2. Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: J Wouter Jukema – Leiden University Medical Center, department of Cardiology
    Co-Author: Hans Vink – Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht, the Netherlands; MicroVascular Health Solutions LLC, Alpine, Utah, USA.
    Co-Author: Bernard M. Van Den Berg – Einthoven Laboratory for Vascular and Regenerative Medicine, Department of Internal Medicine, Nephrology, Leiden University Medical Center, Leiden, the Netherlands.
    Co-Author: Ton J. Rabelink – Einthoven Laboratory for Vascular and Regenerative Medicine, Department of Internal Medicine, Nephrology, Leiden University Medical Center, Leiden, the Netherlands.
    Co-Author: Astrid van Hylckama Vlieg – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: ko Willems van Dijk – 1. Department of Human Genetics, Leiden University Medical Center, Leiden, the Netherlands. 2. Department of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, the Netherlands. 3. Leiden Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, the Netherlands.
    Co-Author: Ruifang Li-Gao – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1104 - Understanding distinct conformational states of full-length coagulation Factor VIII and its complex with vWF : A comprehensive AFM analysis
    Room: Exhibition Hall
    Presenting Author: Samhitha Urs Ramaraje Urs, M.Sc – Institute for Experimental Hematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Jean Luc Pellequer – Univ. Grenoble Alpes, CEA, CNRS, IBS (Institut de Biologie Structurale), F-38000 Grenoble, France
    Co-Author: Jean Marie Teulon – Univ. Grenoble Alpes, CEA, CNRS, IBS (Institut de Biologie Structurale), F-38000 Grenoble, France
    Co-Author: Sneha Singh, PhD – Institute for Experimental Hematology and Transfusion Medicine, University Hospital of Bonn
    Co-Author: Md. Mubasherrul Islam – Institute for Experimental Hematology and Transfusion Medicine, University Hospital Bonn
    Co-Author: Johannes Oldenburg, MD – University Clinic Bonn AöR, Institute of Experimental Haematology and Transfusion Medicine
    Co-Author: Arijit Biswas – Institute for Experimental Hematology and Transfusion Medicine, University Hospital of Bonn
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1105 - Computational Insights into the Interaction between Factor Xa and Tissue Factor Pathway Inhibitor
    Room: Exhibition Hall
    Presenting Author: Dejvid Veizaj – Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands
    Co-Author: Rianne Van Diest – VarmX B.V., Leiden, The Netherlands
    Co-Author: David A. Poole III – AIMMS Division of Molecular Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit, Amsterdam, The Netherlands
    Co-Author: Ka Lei Cheung – Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands
    Co-Author: Pieter Reitsma – Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands
    Co-Author: Daniël Verhoef – Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands
    Co-Author: Daan P. Geerke – AIMMS Division of Molecular Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit, Amsterdam, The Netherlands;
    Co-Author: Mettine H.A Bos, PhD – Dept. Internal Medicine, Div. Thrombosis and Hemostasis, Leiden University Medical Center
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1106 - A novel and versatile platform for high expression of different FVIII modalities
    Room: Exhibition Hall
    Co-Author: Xu Liu – Neoletix Biotech
    Co-Author: Yang-li Lu – Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.
    Co-Author: Yi Zhou – Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.
    Co-Author: zhijun Wang – Neoletix Biotech
    Co-Author: Xiao-zhou Wang – Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.
    Co-Author: Qianhui Li – Neoletix Biotech
    Co-Author: Yu He – Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.
    Co-Author: Lin-feng Wu – Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd.
    Presenting Author: Qi Li – Neoletix Biotech
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1107 - Specific Mutations in Blood Coagulation Factor VIII Have a Cumulative Effect for Increasing its Secretion
    Room: Exhibition Hall
    Co-Author: Bo Shi – U.S. Food and Drug Administration
    Co-Author: Leonid Parunov, PhD – US Food and Drug Administration
    Co-Author: Philip Olivares – U.S. Food and Drug Administration
    Co-Author: Yideng Liang – US Food and Drug Administration
    Co-Author: Haarin Chun – U.S. Food and Drug Administration
    Co-Author: Svetlana A. Shestopal – U.S. Food and Drug Administration
    Co-Author: Abu Hasanat Md Zulfiker – U.S. Food and Drug Administration
    Presenting Author: Andrey G. Sarafanov, PhD – U.S. Food and Drug Administration
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1108 - Ordered cleavage of prothrombin by Hopsarin D in the absence of membranes
    Room: Exhibition Hall
    Presenting Author: Fatma Isik Ustok, PhD – University of Cambridge
    Co-Author: Ty Adams – Cambridge Protein Works Ltd.
    Co-Author: Anna Maywar – University of Cambridge
    Co-Author: James A. Huntington, PhD – University of Cambridge
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1109 - In silico modeling of factor Xa – prothrombin complexes using AlphaFold-Multimer and Molecular Dynamics simulations for functional prediction
    Room: Exhibition Hall
    Presenting Author: Dejvid Veizaj – Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands
    Co-Author: Rianne Van Diest – VarmX B.V., Leiden, The Netherlands
    Co-Author: David A. Poole III – AIMMS Division of Molecular Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit, Amsterdam, The Netherlands
    Co-Author: Ka Lei Cheung – Department of Internal Medicine, Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, the Netherlands
    Co-Author: Pieter Reitsma – Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands
    Co-Author: Daniël Verhoef – Division of Thrombosis and Hemostasis, Einthoven Laboratory for Vascular and Regenerative Medicine, Leiden University Medical Center, Leiden, The Netherlands
    Co-Author: Daan P. Geerke – AIMMS Division of Molecular Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit, Amsterdam, The Netherlands;
    Co-Author: Mettine H.A Bos, PhD – Dept. Internal Medicine, Div. Thrombosis and Hemostasis, Leiden University Medical Center
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1110 - VGA039, a novel anti-Protein S antibody, enhances ex vivo coagulation with hemophilia A blood as assessed by thromboelastometry
    Room: Exhibition Hall
    Presenting Author: Miriam M. Moser – Department of Clinical Pharmacology, Medical University of Vienna
    Co-Author: Lilley Leong – Vega Therapeutics, South San Francisco
    Co-Author: Katarina Kovacevic-Miljevic – Department of Clinical Pharmacology, Medical University of Vienna
    Co-Author: Matthias Weiss-Tessbach – Department of Clinical Pharmacology, Medical University Vienna
    Co-Author: Sandip Panicker – Vega Therapeutics, Inc.
    Co-Author: Benjamin Kim – Vega Therapeutics Inc.
    Co-Author: Daniel Kraemmer, MD – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna
    Co-Author: Katharina Thom – Department of Pediatrics, Medical University of Vienna
    Co-Author: Christoph Male – Department of Paediatrics, Medical University Hospital of Vienna, Vienna, Austria
    Co-Author: Cihan Ay, MD – Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna
    Co-Author: Bernd Jilma, MD – Department of Clinical Pharmacology, Medical University Vienna
    Co-Author: Christian Schoergenhofer, MD, PHD – Department of Clinical Pharmacology, Medical University of Vienna
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1111 - Usefulness of hybrid human-porcine factor VIII for emicizumab-treated patients with hemophilia A and inhibitors
    Room: Exhibition Hall
    Presenting Author: Mitsumasa Osuna, PhD – Department of Pediatrics, Nara Medical University
    Co-Author: Yuto Nakajima, Md.PhD – Department of Pediatrics
    Co-Author: Kuniyoshi mizumachi – Department of Pediatrics, Nara Medical University
    Co-Author: Naruto Shimonishi, MD, PhD – Nara Medical University
    Co-Author: Shoko Furukawa – Departmetn of Pediatrics, Nara Medical University
    Co-Author: Kenichi Ogiwara, MD, PhD – Department of Pediatrics, Nara Medical University
    Co-Author: Keiji Nogami – Nara Medical University, Nara, Japan
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1112 - The procoagulant signature of cancer cells drives fibrin network formation in tumor microenvironment and impacts its quality. Implications in cancer cell migration
    Room: Exhibition Hall
    Co-Author: Chi Mai Tran Huong – Diagnostica STAGO
    Presenting Author: Patrick Van Dreden, PhD – Diagnostica Stago
    Co-Author: eleftheria lefkou – INSERM
    Co-Author: aurélie rousseau – Diagnostica STAGO
    Co-Author: Elisabeth Mbemba – Sorbonne University, Inserm UMR_S_938, Saint-Antoine Research Center, CRSA Paris France
    Co-Author: Noémie Mourot – Sorbonne University, Inserm UMR_S_938, Saint-Antoine Research Center, CRSA, Team "Cancer Biology and Therapeutics", Group "Cancer - Angiogenesis - Haemostasis", Institut Universitaire de Cancérologie, AP-HP, Saint-Antoine Hospital,75012 Paris, France.
    Co-Author: Faltas Beshoy – Sorbonne University, Inserm UMR_S_938, Saint-Antoine Research Center, CRSA, Team "Cancer Biology and Therapeutics", Group "Cancer - Angiogenesis - Haemostasis", Institut Universitaire de Cancérologie, AP-HP, Saint-Antoine Hospital,75012 Paris, France.
    Co-Author: Michéle Sabbah – Sorbonne University, Inserm UMR_S_938, Saint-Antoine Research Center, CRSA, Team "Cancer Biology and Therapeutics", Group "Cancer - Angiogenesis - Haemostasis", Institut Universitaire de Cancérologie, AP-HP, Saint-Antoine Hospital,75012 Paris, France.
    Co-Author: Grigorios Gerotziafas – Sorbonne University, INSERM UMR_S_938, Saint-Antoine Research Center, CRSA, Team "Cancer Biology and Therapeutics", Group "Cancer - Angiogenesis - Haemostasis", Institut Universitaire de Cancérologie, AP-HP, Saint-Antoine Hospital, Paris, France.
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1113 - Exploring the Synergistic Physical-Chemical Factors Behind Anticoagulant Properties in Heparins from Various Animal Sources
    Room: Exhibition Hall
    Presenting Author: Stephan Nicollas M C G de Oliveira, PhD – UFRJ
    Co-Author: Francisco Felipe Bezerra – UFRJ
    Co-Author: Ana M F Tovar – UFF
    Co-Author: Paulo A. S. Mourão – UFRJ
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1114 - Major bleedings in a patient with warfarin hypersensitivity and factor IX propeptide variant, p.Ala37Thr, treated with a direct oral anti Xa inhibitor.
    Room: Exhibition Hall
    Presenting Author: Antonella Tufano, MD, PhD – DEPARTMENT OF CLINICAL MEDICINE AND SURGERY , FEDERICO II UNIVERSITY OF NAPLES
    Co-Author: Carmine Fierarossa – DEPARTMENT OF CLINICAL MEDICINE AND SURGERY. Federico II University of Naples
    Co-Author: Ferdinando Cirillo – DEPARTMENT OF CLINICAL MEDICINE AND SURGERY. Federico II University of Naples
    Co-Author: Ciro Miele – Federico II University of Naples
    Co-Author: Filomena Capasso – 2. UOC Laboratory medicine of hematology and hemostasis; Federico II University Hospital, Naples, Italy
    Co-Author: Luigi Bisceglia – Division of Medical Genetics IRCCS, Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
    Co-Author: Gennaro Vecchione – Division of Medical Genetics IRCCS, Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy
    Co-Author: Ignazio Frangipane – DEPARTMENT OF CLINICAL MEDICINE AND SURGERY. Federico II University of Naples
    Co-Author: Ernesto Cimino – DEPARTMENT OF CLINICAL MEDICINE AND SURGERY. Federico II University of Naples
    Co-Author: Matteo Di Minno – Department of Clinical Medicine and Surgery, Federico II University of Naples, Naples, Italy
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1116 - The associations between sleep health and hemostasis factors in population-based cohort studies
    Room: Exhibition Hall
    Co-Author: Tariq Faquih – 1. Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA. 2. Department of Neurology and Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA. 3. Broad Institute, Cambridge, MA, USA.
    Presenting Author: Jihee Han – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: Renée de Mutsert – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: Raymond Noordam – Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.
    Co-Author: Tamar Sofer – 1. Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA. 2. Department of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA 3. Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA
    Co-Author: Susan Redline – 1. Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA. 2. Department of Neurology and Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA.
    Co-Author: Frits R Rosendaal – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: Ruifang Li-Gao – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Co-Author: Heming Wang – 1. Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA. 2. Department of Neurology and Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, MA, USA. 3. Broad Institute, Cambridge, MA, USA.
    Co-Author: Astrid van Hylckama Vlieg – Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1118 - Evaluation of Normal Pooled Plasma prepared in-house from units of Fresh Frozen Plasma
    Room: Exhibition Hall
    Presenting Author: Sheikha Rashid Al Shiyadi – The Royal Hospital
    Co-Author: Muntadhar Al Moosawi – Royal Hospital
    Co-Author: Noora Said Al Amri – The Royal Hospital
    Co-Author: Ruqaiya Mohammed Al Habsi – The Royal Hospital
    Co-Author: Muna Hashil Al Riyami – The Royal Hospital
    Co-Author: Muhanna Al Musalhi – The Royal Hospital
    Co-Author: Rashid Hafidh Al Ghaithi – Department of Haematology and Blood transfusion, The Royal Hospital
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1119 - The impact of recombinant factor Ⅷ products on inhibitor development in previously untreated and previously treated children with hemophilia A: a systematic review
    Room: Exhibition Hall
    Co-Author: Xiaoqin Feng – Department of Pediatrics, Nanfang Hospital, Southern Medical University
    Co-Author: Xuan Zhou – Department of Hematology, Nanfang Hospital, Southern Medical University
    Presenting Author: Jing Sun, MD – Department of Hematology, Nanfang Hospital, Southern Medical University
    Co-Author: Zhenguo Wang – Medical Affairs, Takeda (China) International Trade Co., Ltd
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1121 - Human missense variants in F3 impair the initiation of blood coagulation
    Room: Exhibition Hall
    Presenting Author: Shabbir A. Ansari, MSc PhD – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School
    Co-Author: James T. Flaumenhaft – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Marisa A. Brake, PhD – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School
    Co-Author: Natasha Panwar – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Nishtha Pathak – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center
    Co-Author: Jacob G. Ludington – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School
    Co-Author: Ernest Turro – Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai
    Co-Author: Sol Schulman, MD, PhD – Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1122 - Regulation of coagulation factor VIII activity in a murine model of steatohepatitis
    Room: Exhibition Hall
    Presenting Author: Morisada Hayakawa, PhD – Department of Biochemistry, School of Medicine, Jichi Medical University
    Co-Author: Yuji Kashiwakura, PhD – Department of Biochemistry, School of Medicine, Jichi Medical University
    Co-Author: Hiroko Hayakawa – Department of Biochemistry, School of Medicine, Jichi Medical University
    Co-Author: Nemekhbayar Baatartsogt, MD, PhD – Department of Biochemistry, School of Medicine, Jichi Medical University
    Co-Author: Nobuhiko Kamoshita – Department of Biochemistry, School of Medicine, Jichi Medical University
    Co-Author: Tsukasa Ohmori – Department of Biochemistry, School of Medicine, Jichi Medical University
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1124 - Effects of 5-azacytidine on zebrafish coagulation
    Room: Exhibition Hall
    Co-Author: Jabila Mary TR – University of North Texas
    Co-Author: Sanchi Dhinoja – University of North Texas
    Presenting Author: Pudur Jagadeeswaran, PhD – University of North Texas
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1126 - Inhibition of the coagulation pathways by Nitroxyl (HNO)
    Room: Exhibition Hall
    Co-Author: Ricardo M. Gomez – Institute of Biotechnology and Molecular Biology, UNLP-CONICET, La Plata, Argentina
    Co-Author: Gala Minsky – Institute of Experimental Medicine, National Academy of Medicine-CONICET
    Co-Author: Santiago Klajnberg – Laboratory of Experimental Thrombosis and Immunobiology of Inflammation, IMEX-CONICET, National Academy of Medicine, Buenos Aires, Argentina
    Co-Author: Fabio Doctorovich – INQUIMAE, Faculty of Exact and Natural Sciences, University of Buenos Aires, C.A.B.A. Argentina.
    Presenting Author: Mirta Schattner, PhD – Laboratory of Experimental Thrombosis and Immunobiology of Inflammation, IMEX-CONICET, National Academy of Medicine, Buenos Aires, Argentina.
    Co-Author: Roberto G. Pozner – Institute of Experimental Medicine, National Academy of Medicine-CONICET
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1127 - Effect of frozen storage conditions of Antithrombin, Protein C, Protein S activity assay stability
    Room: Exhibition Hall
    Co-Author: Houmei Feng – Department of Laboratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China
    Presenting Author: Danyu Song, MM – Department of Laboratory Medicine, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences & Peking Union Medical College Fuwai Hospital
    Co-Author: Yang Zhang – Department of Laboratory Medicine, National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences & Peking Union Medical College Fuwai Hospital
    Coagulation Factors and Co-Factors
  • Tuesday, Jun 25th
    13:45 – 14:45 ICT
    PB1128 - Serial thromboelastography as bleeding and mortality predictors in severe COVID-19 patients
    Room: Exhibition Hall
    Presenting Author: Usi Sukorini, MD, DR – Universitas Gadjah Mada
    Co-Author: Agusta Adipradipta – Unoversitas Gadjah Mada
    Co-Author: Sagita Adventia – Universitas Gadjah Mada
    Co-Author: Annisa Indrarsi – Universitas Gadjah Mada
    Co-Author: Ika Ridlawati – Universitas Gadjah Mada
    Co-Author: Adika Arjana – Universitas Gadjah Mada
    Co-Author: Angeline Purnamasari – Universitas Gadjah Mada
    Coagulation Factors and Co-Factors
  • Wednesday, Jun 26th
    11:00 – 11:15 ICT
    OC 75.4 - Assessing the contribution of (staphylo)coagulases to neutrophil-mediated immunothrombosis
    Room: 111 A-C
    Presenting Author: Sara Zalghout, PhD – Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium
    Co-Author: Mathias Stroobants – Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium
    Co-Author: Caroline Martens – Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium
    Co-Author: Thomas Vanassche – Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium
    Co-Author: Peter Verhamme, MD PhD – Department of Cardiovascular Diseases, University Hospitals Leuven, Leuven, Belgium
    Co-Author: Kimberly Martinod – Center for Molecular and Vascular Biology, Department of Cardiovascular Sciences - KU Leuven (Belgium)
    Coagulation Factors and Co-Factors
  • Wednesday, Jun 26th
    11:15 – 11:30 ICT
    OC 75.5 - Immune modulation by the endothelial protein C receptor (EPCR) in cancer progression
    Room: 111 A-C
    Presenting Author: Jennifer Pott – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Germany
    Co-Author: Sven Pagel – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Germany
    Co-Author: Petra Wilgenbus – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Germany
    Co-Author: Wolfram Ruf – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz
    Co-Author: Claudine Graf, MD PhD – Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Germany
    Coagulation Factors and Co-Factors